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Decreased Immune Activation In Resistance To Hiv-1 Infection Is Associated With An Elevated Frequency Of Cd4(+)cd25(+)foxp3(+) Regulatory T Cells.
(University of Nairobi, 2009-05)
Human immunodeficiency virus (HIV)-resistant commercial sex workers provide a unique opportunity to study correlates of protection associated with natural resistance to HIV infection. Emerging data from studies of these ...
The HAART cell phone adherence trial (WelTel Kenya1): a randomized controlled trial protocol.
(University of Nairobi, 2009-09)
BACKGROUND:
The objectives are to compare the effectiveness of cell phone-supported SMS messaging to standard care on adherence, quality of life, retention, and mortality in a population receiving antiretroviral therapy ...
Sex, microbial translocation, and the African HIV epidemic
(University of Nairobi, 2009-08)
Redd et al. (1) suggest that microbial translocation is not an important contributor to HIV disease progression in Africa, in contrast to its possible role in HIV pathogenesis in North American cohorts (2–4). They further ...
The HAART cell phone adherence trial (WelTel Kenya1): a randomized controlled trial protocol.
(University of Nairobi,, 2009-09)
BACKGROUND:
The objectives are to compare the effectiveness of cell phone-supported SMS messaging to standard care on adherence, quality of life, retention, and mortality in a population receiving antiretroviral therapy ...
Relative HIV Resistance In Kenyan Sex Workers Is Not Due To An Altered Prevalence Or Mucosal Immune Impact Of Herpes Simplex Virus Type 2 Infection.
(University of Nairobi, 2009-09)
Chronic infection by herpes simplex virus type 2 (HSV-2) increases HIV susceptibility, perhaps due to HSV-2-associated increases in activated mucosal immune cells. A small number of Kenyan female sex workers (FSWs) exhibit ...
Elevated elafin/trappin-2 in the female genital tract is associated with protection against HIV acquisition
(2009)
Globally, heterosexual intercourse is the primary route of HIV-1 (HIV) transmission. It follows that mechanisms that protect against HIV infection are likely operative at the genital mucosa. In HIV-resistant Kenyan sex ...
Pyrosequencing of the chaperonin-60 universal target as a tool for determining microbial community composition.
(University of Nairobi, 2009-05)
We compared dideoxy sequencing of cloned chaperonin-60 universal target (cpn60 UT) amplicons to pyrosequencing of amplicons derived from vaginal microbial communities. In samples pooled from a number of individuals, the ...