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Effect of Antiretroviral Therapy on HIV Reservoirs in Elite Controllers.
(University of Nairobi, 2013)
Elite controllers suppress HIV viremia to below the limit of detection in the absence of antiretroviral therapy (ART). However, precise frequencies of CD4+ T cells carrying replication-competent HIV and/or the dynamics of ...
Dislocation of the elbow with ipsilateral forearm fracture. Six particular cases.
(University of Nairobi, 2013-10)
Elbow dislocation associated with ipsilateral radial shaft fracture is an infrequent injury (nine cases reported in the literature). We present six new cases observed between 2006 and 2012, with an average age of 31 years ...
Solitary plasmacytoma of the mandible - a rare entity
(University of Nairobi, 2013)
Plasma cell dyscrasias (multiple myeloma, solitary plasmocytoma of bone and extra medullary plasmocytoma) are cha¬racterized by a monoclonal neoplastic proliferation of plasma cells of which Solitary plasmocytoma of bone ...
Evidence review of hydroxyurea for the prevention of sickle cell complications in low-income countries.
(2013-11)
Hydroxyurea is widely used in high-income countries for the management of sickle cell disease (SCD) in children. In Kenyan clinical guidelines, hydroxyurea is only recommended for adults with SCD. Yet many deaths from SCD ...
Challenges for consent and community engagement in the conduct of cluster randomized trial among school children in low income settings: experiences from Kenya.
(University of Nairobi, 2013)
BACKGROUND:
There are a number of practical and ethical issues raised in school-based health research, particularly those related to obtaining consent from parents and assent from children. One approach to developing, ...
Effects of atropine and propranolol on lung inflammation in experimental envenomation: comparison of two buthidae venoms.
(University of Nairobi, 2013-04)
BACKGROUND:
Previous works had shown that scorpion venom induced neurotransmitter elevation and an inflammatory response associated with various anatomo-pathological modifications. The most dangerous scorpions species ...
Assessment of maternal near-miss and quality of care in a hospital-based study in Accra, Ghana.
(University of Nairobi, 2013)
OBJECTIVE:
To assess the baseline incidence of maternal near-miss, process indicators related to facility access, and quality of care at a tertiary care facility in urban Ghana.
METHODS:
A prospective observational ...
Wilms tumor survival in Kenya.
(University of Nairobi, 2013-06)
PURPOSE:
Survival from Wilms Tumor (WT) exceeds 90% at 5 years in developed nations, whereas at last report, 2-year event-free survival (EFS) in Kenya reached only 35%. To clarify factors linked to these poor outcomes in ...
Primary hydatid cyst of the thigh: on seven cases
(University of Nairobi, 2013-04)
We report on seven cases that presented a benign soft-tissue mass in the thigh muscles. Ultrasonography provided the diagnosis of hydatid cyst. Total pericystecomy was performed. We point out the importance of preoperative ...
Engineered reversal of drug resistance in cancer cells--metastases suppressor factors as change agents.
(University of Nairobi, 2013)
Building molecular correlates of drug resistance in cancer and exploiting them for therapeutic intervention remains a pressing clinical need. To identify factors that impact drug resistance herein we built a model that ...