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Development of a luciferase based viral inhibition assay to evaluate vaccine induced CD8 T-cell responses.
(Universty of Nairobi, 2013-11)
Emergence of SIV and HIV specific CD8 T cells has been shown to correlate with control of in vivo replication. Poor correlation between IFN-γ ELISPOT responses and in vivo control of the virus has triggered the development ...