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Mucosal specimen collection, processing and assay - Experience from a resource-limited setting in Kenya
(University of Nairobi, 2013)
Background:
HIV-1 infection occurs most commonly through
sexual intercourse. Induction of mucosal immune responses will
likely be necessary for an effective HIV vaccine. KAVI embarked
on building capacity for mucosal ...
Development of a luciferase based viral inhibition assay to evaluate vaccine induced CD8 T-cell responses.
(Universty of Nairobi, 2013-11)
Emergence of SIV and HIV specific CD8 T cells has been shown to correlate with control of in vivo replication. Poor correlation between IFN-γ ELISPOT responses and in vivo control of the virus has triggered the development ...