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Determination of midazolam and its major metabolite 1'-hydroxymidazolam by high-performance liquid chromatography-electrospray mass spectrometry in plasma from children
(University of Nairobi, 2005)
We have developed a sensitive, selective and reproducible reversed-phase high-performance liquid chromatography method coupled with electrospray ionization mass spectrometry (HPLC-ESI-MS) for the simultaneous quantification ...
Determination of lorazepam in plasma from children by high-performance liquid chromatography with UV detection
(University of Nairobi, 2005)
A simple, sensitive, selective, and reproducible reversed-phase high-performance liquid chromatographic (HPLC) method with UV detection was developed for the determination of lorazepam (LZP) in human plasma, using oxazepam ...
The quality of sulphadoxine-pyrimethamine and amodiaquine products in the Kenyan retail sector
(University of Nairobi, 2005)
Background and objectives:Malaria is a disease of major public health importance in Kenya killing 26,000 children under 5 years of age annually. This paper seeks to assess the quality of sulphadoxine-pyrimethamine (SP) and ...
Once-daily combination therapy for uncomplicated malaria: is this the way forward?
(University of Nairobi, 2005)
Combination therapy in the treatment of malaria
(University of Nairobi, 2005)
The role of sequential administration of sulphadoxine/pyrimethamine following quinine in the treatment of severe falciparum malaria in children
(University of Nairobi, 2005)
Sulphadoxine/pyrimethamine (SP) is often administered with quinine in the treatment of severe falciparum malaria to shorten the course of quinine. The efficacy of SP alone in the treatment of non-severe malaria has been ...