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Safety and Immunogenicity Study of Multiclade HIV-1 Adenoviral Vector Vaccine Alone or as Boost following a Multiclade HIV-1 DNA Vaccine in Africa
(University of nairobi, 2010)
Abstract
BACKGROUND:
We conducted a double-blind, randomized, placebo-controlled Phase I study of a recombinant replication-defective adenovirus type 5 (rAd5) vector expressing HIV-1 Gag and Pol from subtype B and Env ...
Personality disorder: a new global perspective.
(University of Nairobi, 2010-02)
Personality disorder is now being accepted as an important condition in mainstream psychiatry across the world. Although it often remains unrecognized in ordinary practice, research studies have shown it is common, creates ...
Salivary Antimicrobial Peptides As Potential Biomarkers Of Periodontal Disease
(University of Nairobi, 2010-07)
Objectives: Using SELDI-TOF-MS we have previously identified putative salivary biomarkers of periodontitis. Some of these identified peaks were predicted to be antimicrobial peptides (AMPs), specifically alpha defensins ...
An autopsy case of sudden unexplained death caused by malaria.
(University of Nairobi, 2010)
Sudden unexplained deaths, especially those unwitnessed can lead to forensic issues and would necessitate the need for a meticulous and complete postmortem examination including ancillary investigations to discover the ...
Postmortem diagnosis of acute haemorrhagic pancreatitis.
(University of Nairobi, 2010)
Forensic pathologists can help in the investigation of sudden unexpected deaths in co-operation with the officials responsible for the maintenance of law and order to administer justice. Sudden unexpected deaths form the ...
Inhibition of double-stranded RNA-dependent protein kinase strongly decreases cytokine production and release in peripheral blood mononuclear cells from patients with Alzheimer's disease.
(University of Nairobi, 2010)
Alzheimer's disease (AD), a neurodegenerative disorder, is the most common form of dementia in the elderly individuals. Among the pathogenic mechanisms in AD, chronic systemic inflammation is described and characterized ...
Neuronal hypertrophy and mast cells in histologically negative, clinically diagnosed acute appendicitis: a quantitative immunophenotypical analysis.
(University of Nairobi, 2010)
INTRODUCTION AND AIM:
In about 20-25% of appendicectomies performed for clinically suspected acute appendicitis, definite morphological changes are lacking on histopathological examination. The present study was done ...
Is the Pedestrian an Endangered Road User? A Descriptive Account of Pedestrian Musculoskeletal Injuries
(2010)
Background: Trauma is a leading cause of morbidity and mortality in Africa. Road traffic crashes are
causative in majority of these cases. Pedestrians are vulnerable to injury in all types of collisions.
This paper ...
Comparative functional structure of the olfactory mucosa in the domestic dog and sheep.
(2010)
Olfactory acuity differs among animal species depending on age and dependence on smell. However, the attendant functional anatomy has not been elucidated. We sought to determine the functional structure of the olfactory ...
Identification and characterization of HLA-A*0301 epitopes in HIV-1 gag proteins using a novel approach
(2010-01)
Identification of CTL epitopes correlated to immune protection is important for the development of vaccines that enhance T-cell mediated immune responses. The correlation of positively selected amino acids (PS) of HIV-1 ...