Mitochondrial oxidation rates and enzyme activities in the liver and brain of vitamin B12-deficient baboons
| dc.contributor.author | Deana, R | |
| dc.contributor.author | Pearson, DJ | |
| dc.contributor.author | Siddons, RC | |
| dc.contributor.author | Verjee, ZH | |
| dc.date.accessioned | 2015-07-20T13:32:05Z | |
| dc.date.available | 2015-07-20T13:32:05Z | |
| dc.date.issued | 1975 | |
| dc.identifier.citation | International Journal of Biochemistry 1975 Vol. 6 No. 7 pp. 467-470 | en_US |
| dc.identifier.uri | http://www.cabdirect.org/abstracts/19751435636.html?resultNumber=7&q=au%3A%22Verjee%2C+Z.+H.%22 | |
| dc.identifier.uri | http://hdl.handle.net/11295/88332 | |
| dc.description.abstract | Brain and liver samples were taken from 7 adult male Papio anubis after 32 months on a vitamin B-12 deficient diet of starch, sucrose, heated soya bean meal, cellulose, maize oil, mineral and vitamin supplements and ampicillin 50 mg/kg; 4 controls on the same diet received 2 mu g cyanocobalamin daily. In liver mitochondria of deprived baboons, propionyl-carnitine oxidation was unchanged whereas oxidation rates of other substrates, in particular succinate and heptanoate, were higher than those of controls; mitochondrial oxidation rates tended to be lower in brain of deprived baboons. Lipogenic enzymes were not significantly different in deprived and control baboons; acetylcholinesterase was unchanged in liver, but decreased in the brain of animals deprived of vitamin B-12. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | University of Nairobi | en_US |
| dc.title | Mitochondrial oxidation rates and enzyme activities in the liver and brain of vitamin B12-deficient baboons | en_US |
| dc.type | Article | en_US |
| dc.type.material | en | en_US |
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