Activated T lymphocytes in infiltrates and draining lymph nodes of nasopharyngeal carcinoma
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Date
1980Author
Uri, Galili
Eva, Klein
George, Klein
Singh, Inderjit
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Lymphocytes isolated from the tumors and draining lymph nodes of nasopharyngeal carcinoma (NPC) patients exhibit the following characteristics of immune activation: (1) stable E rosette formation, (2) natural attachment to various human cells, (3) sensitivity in vitro to the lytic effect of glucocorticoids. Although the NPC T cells attach in vitroto various cells they kill only EBV-genome-carrying targets. These findings suggest the occurrence of a local cellular immune response in NPC, possibly directed to EBV-determined antigens.
URI
http://onlinelibrary.wiley.com/doi/10.1002/ijc.2910250111/abstract?systemMessage=Wiley+Online+Library+will+have+be+unavailable+on+Saturday+5th+December+from+10%3A00-14%3A00+GMT+%2F+05%3A00-09%3A00+EST+%2F+18%3A00-22%3A00+SGT+for+essential+maintenance.+Apologies+for+the+inconvenience.http://hdl.handle.net/11295/92787
Citation
Galili, Uri, et al. "Activated T lymphocytes in infiltrates and draining lymph nodes of nasopharyngeal carcinoma." International Journal of Cancer 25.1 (1980): 85-89.Publisher
University of Nairobi
Collections
- Faculty of Health Sciences (FHS) [10387]