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A common CD4 gene variant Is associated with an increased risk of HIV-1 infection in Kenyan female commercial sex workers

dc.contributor.authorOyugi, Julius O.
dc.contributor.authorVouriot, Françoise C. M.
dc.contributor.authorAlimonti, Judie
dc.contributor.authorWayne, Stephen
dc.contributor.authorLuo, Ma
dc.contributor.authorLand, Allison M.
dc.contributor.authorAO, Zhujun
dc.contributor.authorYao, Xiaojian
dc.contributor.authorSekaly, Rafick P.
dc.contributor.authorElliott, Lawrence J.
dc.contributor.authorSimonsen, J. Neil
dc.contributor.authorBall, T. Blake
dc.contributor.authorJaoko Walter G.
dc.contributor.authorKimani, Joshua
dc.contributor.authorPlummer, Francis A.
dc.contributor.authorFowke, Keith R.
dc.date.accessioned2013-02-18T11:43:40Z
dc.date.issued2009
dc.identifier.citationCD4 Polymorphism and HIV-1 Infectionen
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/pubmed/19301975
dc.identifier.urihttp://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/10111
dc.description.abstractIt has been predicted that CD4 C868T, a novel CD4 single-nucleotide polymorphism (SNP) that has been found to be highly prevalent among Africans, changes the tertiary structure of CD4, which may alter susceptibility to human immunodeficiency virus (HIV) infection. Overall, the present study found a strong correlation between CD4 C868T and increased susceptibility to HIV-1 infection. Given the high prevalence of both HIV infection and CD4 C868T in African populations, the effect of this SNP on the epidemic in Africa could be dramaticen
dc.language.isoenen
dc.titleA common CD4 gene variant Is associated with an increased risk of HIV-1 infection in Kenyan female commercial sex workersen
dc.typeArticleen


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