Translactonization in Erythromycins
dc.contributor.author | Kibwage, IO | |
dc.contributor.author | Busson, R | |
dc.contributor.author | Janssen, G | |
dc.contributor.author | Hoogmartens, J | |
dc.contributor.author | Vanderhaeghe, H | |
dc.date.accessioned | 2013-02-19T09:48:37Z | |
dc.date.issued | 1987 | |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/10248 | |
dc.description.abstract | When erythromycin A is heated in diethylamine-acetic acid. an erythromycin hemiketal is obtained, which can be further transformed into a new enol ether and spiroketal. The new euol ether is also obtained in equilibrium with the normal one on heating erythromycin A or B in pyridine-acetic acid. The novel compounds. which will be called pseudoerythromycin derivatives. are characterized by a translactonization between the eu-hydroxyl and the lactone group. Their structure was proved by mass and IH and 13C NMR spectrometry. by acetylation experiments, and by degradation with lead tetraacetate. | en |
dc.language.iso | en | en |
dc.title | Translactonization in Erythromycins | en |
dc.type | Article | en |
local.embargo.terms | 6 months | en |
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