Translactonization in Erythromycins

dc.contributor.author	Kibwage, IO
dc.contributor.author	Busson, R
dc.contributor.author	Janssen, G
dc.contributor.author	Hoogmartens, J
dc.contributor.author	Vanderhaeghe, H
dc.date.accessioned	2013-02-19T09:48:37Z
dc.date.issued	1987
dc.identifier.uri	http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/10248
dc.description.abstract	When erythromycin A is heated in diethylamine-acetic acid. an erythromycin hemiketal is obtained, which can be further transformed into a new enol ether and spiroketal. The new euol ether is also obtained in equilibrium with the normal one on heating erythromycin A or B in pyridine-acetic acid. The novel compounds. which will be called pseudoerythromycin derivatives. are characterized by a translactonization between the eu-hydroxyl and the lactone group. Their structure was proved by mass and IH and 13C NMR spectrometry. by acetylation experiments, and by degradation with lead tetraacetate.	en
dc.language.iso	en	en
dc.title	Translactonization in Erythromycins	en
dc.type	Article	en
local.embargo.terms	6 months	en