Quality of phenoxymethylpenicillin dry suspensions
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Date
1991Author
Kibwage, IO
Vugigi, S
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
The antibiotic phenoxymethylpenicillin (penicillin V) is still a drug of choice as a prophylactic agent in rheumatic fever and in the treatment of otitis rneolo.ervslpelos and tonsillitis. Penicillin V is composed of the biologically important fused thiozolidine and beta-Iactam rings. These rings are unstable in aqueous media both at low and high pH values wherein they undergo hydrolysis as shown in Figure 1. The hydrolytic products have no antibacterial activity.
Publisher
Drug Analysis and Research Unit. University of Nairobi
Collections
- Faculty of Health Sciences (FHS) [10377]