Global Distribution of Human Protoparvoviruses
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Date
2018-07-07Author
Väisänen, E
Mohanraj, U
Kinnunen, PM
Jokelainen, P
Al-Hello, H
Barakat, AM
Sadeghi, M
Jalilian, FA
Majlesi, A
Masika, M
Mwaengo, D
Anzala, O
Delwart, E
Vapalahti, O
Hedman, K
Söderlund-Venermo, M
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Development of next-generation sequencing and metagenomics has revolutionized detection of novel viruses. Among these viruses are 3 human protoparvoviruses: bufavirus, tusavirus, and cutavirus. These viruses have been detected in feces of children with diarrhea. In addition, cutavirus has been detected in skin biopsy specimens of cutaneous T-cell lymphoma patients in France and in 1 melanoma patient in Denmark. We studied seroprevalences of IgG against bufavirus, tusavirus, and cutavirus in various populations (n = 840), and found a striking geographic difference in prevalence of bufavirus IgG. Although prevalence was low in adult populations in Finland (1.9%) and the United States (3.6%), bufavirus IgG was highly prevalent in populations in Iraq (84.8%), Iran (56.1%), and Kenya (72.3%). Conversely, cutavirus IgG showed evenly low prevalences (0%-5.6%) in all cohorts, and tusavirus IgG was not detected. These results provide new insights on the global distribution and endemic areas of protoparvoviruses.
Citation
Emerg Infect Dis. 2018 Jul;24(7):1292-1299Publisher
BMC
Collections
- Faculty of Health Sciences (FHS) [10378]