BioMedical Journal Articles
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High Multiple Carriage and Emergence of Streptococcus Pneumoniae Vaccine Serotype Variants in Malawian Children
(University of Nairobi, 2015)Background: Carriage of either single or multiple pneumococcal serotypes (multiple carriage) is a prerequisite for developing invasive pneumococcal disease. However, despite the reported high rates of pneumococcal carriage ... -
Comment on “Encephalopathy in patients with COVID‐19: A review”
(John Wiley & Sons, 2020-06-30) -
Responding to maternal, neonatal and child health equipment needs in Kenya: a model for an innovation ecosystem leveraging on collaborations and partnerships
(BMJ, 2020-04-24)Background Up to 70% of medical devices in low-income and middle-income countries are partially or completely non-functional, impairing service provision and patient outcomes. In Sub-Saharan Africa, medical devices not ... -
Molecular prevalence of emerging Anaplasma and Ehrlichia pathogens in apparently healthy dairy cattle in peri-urban Nairobi, Kenya
(BMC Veterinary Research, 2020-09-29)Background Anaplasma and Ehrlichia species are tick-borne pathogens of both veterinary and public health importance. The current status of these pathogens, including emerging species such as Ehrlichia minasensis and ... -
Knowledge, practices and perceptions of trachoma and its control among communities of Narok County, Kenya
(Springer, 2016-07)Background Trachoma is the leading infectious cause of blindness in the world. It is commonly found in cultural groups with poor hygiene. Trachoma control includes Surgery, Antibiotics, Facial cleanliness and Environmental ... -
Antibacterial activities of the methanol extracts and compounds from Erythrina sigmoidea against Gram-negative multi-drug resistant phenotypes.
(University of Nairobi, 2015-12)Background: In the present study, the methanol extracts from the leaves, as well as compounds namely sigmoidin I (1), atalantoflavone (2), bidwillon A (3), neocyclomorusin (4), 6α-hydroxyphaseollidin (5) and neobavaisof ... -
The burden of unrecognised chronic kidney disease in patients with type 2 diabetes at a county hospital clinic in Kenya : implications to care and need for screening
(BioMed Central, 2020-01)Background Chronic Kidney Disease (CKD) in patients with type 2 diabetes enhances the cardiovascular risk profiles and disease, and is a strong predictor of progression to end-stage kidney disease. Early diagnosis is ... -
Burden of prehypertension among adults in Kenya: a retrospective analysis of findings from the Healthy Heart Africa (HHA) Programme
(BioMed Central, 2020-03)Background Hypertension is the leading risk factor for mortality globally. African countries, including Kenya, have a high and rising prevalence of hypertension. Prehypertension is associated with an increased risk of ... -
Shifting parental roles, caregiving practices and the face of child development in low resource informal settlements of Nairobi: experiences of community health workers and school teachers
(Springer Nature, 2018-11-26)Approximately, 42% of the Kenyan population live below the poverty line. Rapid growth and urbanization of Kenya’s population have resulted in a changing poverty and food security environment in high-density urban areas. ... -
A cross-sectional study of depression with comorbid substance use dependency in pregnant adolescents from an informal settlement of Nairobi: drawing implications for treatment and prevention work
(Springer Nature, 2018-12-20)Introduction Adolescent pregnancy is a highly prevalent and significant public health problem in Kenya, and mental health needs of pregnant adolescent girls have been overlooked. Nearly, 50% of the world’s population ... -
Mechanisms associated with maternal adverse childhood experiences on offspring’s mental health in Nairobi informal settlements: a mediational model testing approach
(BioMed Central, 2018-12-05)Background Adverse childhood experiences (ACEs) is a significant public health and social welfare problem in low-and middle income countries (LMICs). However, most ACEs research is based on developed countries, and little ... -
Factors affecting HBV vaccination in a Medical training College in Kenya: A mixed methods Study
(Sringer Nature, 2020-01-13)Abstract Background: Hepatitis B Virus (HBV) is highly endemic in Sub-Saharan Africa with 70 to 90% of the population becoming infected before the age of 40 years. Healthcare workers (HCWs) including healthcare students ... -
Efficacy of a group tobacco cessation behavioral intervention among tobacco users with concomitant mental illness in Kenya: protocol for a controlled clinical trial
(BMC Public Health, 2019-12)Background The rate of tobacco use among people with mental illness is nearly twice that of the general population. Psychotropic medications for tobacco cessation are relatively expensive for most Kenyans. Behavioral ... -
Prevalence and risk factors of three curable sexually transmitted infections among women in Nairobi, Kenya
(http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812604/, 2016-03)Background Sexually transmitted infections (STIs) are a major public health problem, especially in developing countries. The complications of untreated STIs in the female genital tract and their role in adverse pregnancy ... -
Building capacity in implementation science research training at the University of Nairobi
(Univeraity of Nanirobi, 2016-03-08)Background: Health care systems in sub-Saharan Africa, and globally, grapple with the problem of closing the gap between evidence-based health interventions and actual practice in health service settings. It is essential ... -
Predicted HIV-1 coreceptor usage among Kenya patients shows a high tendency for subtype d to be cxcr4 tropic
(2012-07-28)Abstract Background CCR5 antagonists have clinically been approved for prevention or treatment of HIV/AIDS. Countries in Sub-Saharan Africa with the highest burden of HIV/AIDS ... -
Feasibility of an innovative electronic mobile system to assist health workers to collect accurate, complete and timely data in a malaria control programme in a remote setting in Kenya
(2015-11-04)Abstract Background The cornerstone of decision making aimed at improving health services is accurate and timely health information. The Ministry of Public Health and Sanitation ... -
Alcohol consumption and hazardous drinking in western Kenya—a household survey in a health and demographic surveillance site
(2015-09-25)Abstract Background Alcohol use and hazardous drinking have been studied in school children and in urban areas of Kenya, but there has been no adult survey of these issues in ... -
Innovative tools and OpenHDS for health and demographic surveillance on Rusinga Island, Kenya
(2015-09-01)Abstract Background Health in low and middle income countries is on one hand characterized by a high burden associated with preventable communicable diseases and on the other ... -
Impact of highly active antiretroviral therapy on hematological indices among HIV-1 infected children at Kenyatta National Hospital-Kenya: retrospective study.
(University of Nairobi, 2015)BACKGROUND: HIV infected children experience a range of hematological complications which show marked improvement within 6 months of initiating anti-retroviral therapy. The Objectives of the study was to describe the ...
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