BioMedical Journal Articles
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Prevalence and risk factors of three curable sexually transmitted infections among women in Nairobi, Kenya
(http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812604/, 2016-03)Background Sexually transmitted infections (STIs) are a major public health problem, especially in developing countries. The complications of untreated STIs in the female genital tract and their role in adverse pregnancy ... -
Building capacity in implementation science research training at the University of Nairobi
(Univeraity of Nanirobi, 2016-03-08)Background: Health care systems in sub-Saharan Africa, and globally, grapple with the problem of closing the gap between evidence-based health interventions and actual practice in health service settings. It is essential ... -
Predicted HIV-1 coreceptor usage among Kenya patients shows a high tendency for subtype d to be cxcr4 tropic
(2012-07-28)Abstract Background CCR5 antagonists have clinically been approved for prevention or treatment of HIV/AIDS. Countries in Sub-Saharan Africa with the highest burden of HIV/AIDS ... -
Feasibility of an innovative electronic mobile system to assist health workers to collect accurate, complete and timely data in a malaria control programme in a remote setting in Kenya
(2015-11-04)Abstract Background The cornerstone of decision making aimed at improving health services is accurate and timely health information. The Ministry of Public Health and Sanitation ... -
Alcohol consumption and hazardous drinking in western Kenya—a household survey in a health and demographic surveillance site
(2015-09-25)Abstract Background Alcohol use and hazardous drinking have been studied in school children and in urban areas of Kenya, but there has been no adult survey of these issues in ... -
Innovative tools and OpenHDS for health and demographic surveillance on Rusinga Island, Kenya
(2015-09-01)Abstract Background Health in low and middle income countries is on one hand characterized by a high burden associated with preventable communicable diseases and on the other ... -
Impact of highly active antiretroviral therapy on hematological indices among HIV-1 infected children at Kenyatta National Hospital-Kenya: retrospective study.
(University of Nairobi, 2015)BACKGROUND: HIV infected children experience a range of hematological complications which show marked improvement within 6 months of initiating anti-retroviral therapy. The Objectives of the study was to describe the ... -
A review of the pattern of AIDS defining, HIV associated neoplasms and premalignant lesions diagnosed from 2000–2011 at Kenyatta National Hospital, Kenya
(2015-08-24)Abstract Background Sub-Sahara Africa hosts up to 71 % of all HIV infected people in the world. With this high incidence of Human immunodeficiency virus ( HIV) comes the burden ... -
Tedium vitae, death wishes, suicidal ideation and attempts in Kenya-prevalence and risk factors
(2015-08-08)Abstract Background There has been no previous household population study of suicidal ideation and attempts in Kenya. Therefore this study aimed to establish the prevalence ... -
HIV-1 Tat induces DNMT over-expression through microRNA dysregulation in HIV-related non Hodgkin lymphomas
(2014-12-09)Abstract Background A close association between HIV infection and the development of cancer exists. Although the advent of highly active antiretroviral therapy has changed the ... -
Sero-epidemiology of Peste des petits ruminants virus infection in Turkana County, Kenya
(2015-04-08)Abstract Background Peste des petits ruminants (PPR) is a contagious viral disease of small ruminants. Serum samples from sheep (n = 431) and goats (n = 538) of all ages were ... -
Pharmacological evidence for the folk use of Nefang: antipyretic, anti-inflammatory and antinociceptive activities of its constituent plants
(2015-06-09)Abstract Background Nefang is a polyherbal anti-malarial composed of Mangifera indica ( MiB and MiL; bark and leaf), Psidium guajava ( ... -
The accountability for reasonableness approach to guide priority setting in health systems within limited resources – findings from action research at district level in Kenya, Tanzania, and Zambia
(2014-08-20)Abstract Background Priority-setting decisions are based on an important, but not sufficient set of values and thus lead to disagreement on priorities. Accountability for ... -
Application of principal component analysis to multispectral-multimodal optical image analysis for malaria diagnostics
(2014-12-11)Abstract Background Multispectral imaging microscopy is a novel microscopic technique that integrates spectroscopy with optical imaging to record both spectral and spatial ... -
Effects of HIV-1 infection on malaria parasitemia in milo sub-location, western Kenya
(2015-07-15)Abstract Background Malaria and HIV infections are both highly prevalent in sub-Saharan Africa, with HIV-infected patients being at higher risk of acquiring malaria. HIV-1 ... -
Relationship between anthropometric measures and early electrocardiographic changes in obese rats
(2014-12-18)Abstract Background The degree of cardiovascular function impairment parallels the degree of obesity and obese subjects have abnormal changes on the electrocardiogram (ECG). ... -
Prevalence of malaria parasites in adults and its determinants in malaria endemic area of Kisumu County, Kenya
(2015-07-08)Abstract Background The prevalence of malaria parasites in adults in Africa is less well researched than in children. Therefore, a demographic surveillance site was used to ... -
Parasites and vectors of malaria on Rusinga Island, Western Kenya
(2015-04-28)Abstract Background There is a dearth of information on malaria endemicity in the islands of Lake Victoria in western Kenya. In this study malaria prevalence and Plasmodium ... -
Cytochrome P450 2B6 genetic variants are associated with plasma nevirapine levels and clinical response in HIV-1 infected Kenyan women: a prospective cohort study
(2015-04-15)Abstract Background Polymorphisms in cytochrome P450 2B6 (CYP2B6) affect the steady state plasma concentration of nevirapine. CYP2B6 516G>T and 983T>C are common in African ... -
Parasite accumulation in placenta of non-immune baboons during Plasmodium knowlesi infection
(2015-03-18)Abstract Background Placental malaria (PM) causes adverse pregnancy outcomes in the mother and her foetus. It is difficult to study PM directly in humans due to ethical ...
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