BioMedical Journal Articles

Knowledge, practices and perceptions of trachoma and its control among communities of Narok County, Kenya

Njomo, Doris W.; Karimurio, Jefitha; Odhiambo, Gladys O. (Springer, 2016-07)

Background Trachoma is the leading infectious cause of blindness in the world. It is commonly found in cultural groups with poor hygiene. Trachoma control includes Surgery, Antibiotics, Facial cleanliness and Environmental ...

Antibacterial activities of the methanol extracts and compounds from Erythrina sigmoidea against Gram-negative multi-drug resistant phenotypes.

Unknown author (University of Nairobi, 2015-12)

Background: In the present study, the methanol extracts from the leaves, as well as compounds namely sigmoidin I (1), atalantoflavone (2), bidwillon A (3), neocyclomorusin (4), 6α-hydroxyphaseollidin (5) and neobavaisof ...

The burden of unrecognised chronic kidney disease in patients with type 2 diabetes at a county hospital clinic in Kenya : implications to care and need for screening

Otieno, Frederick. C. F; Ogola, E. N.; Kimando, M. W.; Mutai, K. (BioMed Central, 2020-01)

Background Chronic Kidney Disease (CKD) in patients with type 2 diabetes enhances the cardiovascular risk profiles and disease, and is a strong predictor of progression to end-stage kidney disease. Early diagnosis is ...

Burden of prehypertension among adults in Kenya: a retrospective analysis of findings from the Healthy Heart Africa (HHA) Programme

Mecha, Jared O.; Kubo, E. N.; Odhiambo, C. O.; Kinoti, F. G.; Njau, K.; Yonga, G; Ogola, E.N. (BioMed Central, 2020-03)

Background Hypertension is the leading risk factor for mortality globally. African countries, including Kenya, have a high and rising prevalence of hypertension. Prehypertension is associated with an increased risk of ...

Shifting parental roles, caregiving practices and the face of child development in low resource informal settlements of Nairobi: experiences of community health workers and school teachers

Kumar, M.; Madeghe, B.; Osok-Waudo, J; Wambua, Grace N; Amugune, Beatrice K (Springer Nature, 2018-11-26)

Approximately, 42% of the Kenyan population live below the poverty line. Rapid growth and urbanization of Kenya’s population have resulted in a changing poverty and food security environment in high-density urban areas. ...

A cross-sectional study of depression with comorbid substance use dependency in pregnant adolescents from an informal settlement of Nairobi: drawing implications for treatment and prevention work

Kimbui, E.; Kuria, M.; Yator, O; Kumar, M (Springer Nature, 2018-12-20)

Introduction Adolescent pregnancy is a highly prevalent and significant public health problem in Kenya, and mental health needs of pregnant adolescent girls have been overlooked. Nearly, 50% of the world’s population ...

Mechanisms associated with maternal adverse childhood experiences on offspring’s mental health in Nairobi informal settlements: a mediational model testing approach

Kumar, M.; Amugune, B.; Madeghe, B (BioMed Central, 2018-12-05)

Background Adverse childhood experiences (ACEs) is a significant public health and social welfare problem in low-and middle income countries (LMICs). However, most ACEs research is based on developed countries, and little ...

Factors affecting HBV vaccination in a Medical training College in Kenya: A mixed methods Study

Maina, Anne N.; Bii, Leah C. (Sringer Nature, 2020-01-13)

Abstract Background: Hepatitis B Virus (HBV) is highly endemic in Sub-Saharan Africa with 70 to 90% of the population becoming infected before the age of 40 years. Healthcare workers (HCWs) including healthcare students ...

Efficacy of a group tobacco cessation behavioral intervention among tobacco users with concomitant mental illness in Kenya: protocol for a controlled clinical trial

Olando, Y.; Kuria, M.; Mathai, M.; Huffman, M. D (BMC Public Health, 2019-12)

Background The rate of tobacco use among people with mental illness is nearly twice that of the general population. Psychotropic medications for tobacco cessation are relatively expensive for most Kenyans. Behavioral ...

Prevalence and risk factors of three curable sexually transmitted infections among women in Nairobi, Kenya

Maina, Anne Njeri; Kimani, Joshua; Anzala, Omu (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812604/, 2016-03)

Background Sexually transmitted infections (STIs) are a major public health problem, especially in developing countries. The complications of untreated STIs in the female genital tract and their role in adverse pregnancy ...

Building capacity in implementation science research training at the University of Nairobi

Osanjo, George O.; Oyugi, Julius O.; . Kibwage, Isaac O; Mwanda, Walter O.; Ngugi, Elizabeth N; Otieno, Fredrick C.; Ndege, Wycliffe; Child, Mara; [et.al] (Univeraity of Nanirobi, 2016-03-08)

Background: Health care systems in sub-Saharan Africa, and globally, grapple with the problem of closing the gap between evidence-based health interventions and actual practice in health service settings. It is essential ...

Predicted HIV-1 coreceptor usage among Kenya patients shows a high tendency for subtype d to be cxcr4 tropic

Wambui, Veronica; Kiptoo, Michael; Kinyua, Joyceline; Odera, Irene; Muge, Edward; Muiruri, Peter; Lihana, Raphael; Kinyanjui, Peter; Songok, Elijah M (2012-07-28)

Abstract Background CCR5 antagonists have clinically been approved for prevention or treatment of HIV/AIDS. Countries in Sub-Saharan Africa with the highest burden of HIV/AIDS ...

Feasibility of an innovative electronic mobile system to assist health workers to collect accurate, complete and timely data in a malaria control programme in a remote setting in Kenya

Soti, David O; Kinoti, Stephen N; Omar, Ahmeddin H; Logedi, John; Mwendwa, Teresa K; Hirji, Zahra; Ferro, Santiago (2015-11-04)

Abstract Background The cornerstone of decision making aimed at improving health services is accurate and timely health information. The Ministry of Public Health and Sanitation ...

Alcohol consumption and hazardous drinking in western Kenya—a household survey in a health and demographic surveillance site

Jenkins, Rachel; Othieno, Caleb; Ongeri, Linnet; Kiima, David; Sifuna, Peter; Kingora, James; Omollo, Raymond; Ogutu, Bernhards (2015-09-25)

Abstract Background Alcohol use and hazardous drinking have been studied in school children and in urban areas of Kenya, but there has been no adult survey of these issues in ...

Innovative tools and OpenHDS for health and demographic surveillance on Rusinga Island, Kenya

Homan, Tobias; Di Pasquale, Aurelio; Kiche, Ibrahim; Onoka, Kelvin; Hiscox, Alexandra; Mweresa, Collins; Mukabana, Wolfgang R; Takken, Willem; Maire, Nicolas (2015-09-01)

Abstract Background Health in low and middle income countries is on one hand characterized by a high burden associated with preventable communicable diseases and on the other ...

Impact of highly active antiretroviral therapy on hematological indices among HIV-1 infected children at Kenyatta National Hospital-Kenya: retrospective study.

Kibaru, EG; Nduati, R; Wamalwa, D; Kariuki, N (University of Nairobi, 2015)

BACKGROUND: HIV infected children experience a range of hematological complications which show marked improvement within 6 months of initiating anti-retroviral therapy. The Objectives of the study was to describe the ...

A review of the pattern of AIDS defining, HIV associated neoplasms and premalignant lesions diagnosed from 2000–2011 at Kenyatta National Hospital, Kenya

Rogena, Emily A; Simbiri, Kenneth O; De Falco, G.; Leoncini, L.; Ayers, Leona; Nyagol, J. (2015-08-24)

Abstract Background Sub-Sahara Africa hosts up to 71 % of all HIV infected people in the world. With this high incidence of Human immunodeficiency virus ( HIV) comes the burden ...