Types and prevalence of HIV-related opportunistic infections/conditions among HIV-positive patients attending Kenyatta National Hospital in Nairobi, Kenya
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Date
2020Author
Chepkondol, Geoffrey K
Jolly, Pauline E
Yatich, Nelly
Mbowe, Omar
Jaoko, Walter G
Type
ArticleLanguage
enMetadata
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Background: Although antiretroviral therapy (ART) has resulted in significant decrease in opportunistic infections (OIs), OIs continue to cause significant morbidity and mortality among HIV patients.
Objective: To determine the prevalence and types of HIV/AIDS-related OIs among patients attending Kenyatta National Hospital (KNH) in Nairobi, Kenya.
Methods: A cross-sectional study was conducted from May to August 2010 among patients ≥19 years. An interviewer-ad- ministered questionnaire was used to collect data on socio-demographic factors, HIV and OIs. CD4 data were extracted from clinical records.
Results: Most patients (72%) had lived with HIV for ≤ 5 years and 78.8% had an OI. The 3 most common OIs were TB (35%), Herpes Zoster (HZ; 15.4%) and oral thrush (OT; 8%). Years of HIV infection significantly predicted TB (p=0.01). Patients with CD4 ≤ 349 were almost twice as likely to have TB, than those with CD4 ≥500. Type of occupation predicted OT (p=0.04) with skilled workers less likely to have OT. Patients with primary/vocational/technical education were >3 times more likely to have HZ than those with tertiary education.
Conclusion: Due to the complex management of HIV and its associated OIs, appropriate implementation of the recom- mended guidelines for care and prevention among patients at KNH is important.
URI
https://www.ajol.info/index.php/ahs/article/view/197826http://erepository.uonbi.ac.ke/handle/11295/153442
Publisher
University of Nairobi
Rights
Attribution-NonCommercial-NoDerivs 3.0 United StatesUsage Rights
http://creativecommons.org/licenses/by-nc-nd/3.0/us/Collections
- Faculty of Health Sciences (FHS) [10378]
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