Effectiveness of veno-occlusion with lignocaine for prevention of propofolinduced vascular pain at the Kenyatta National Hospital.
Abstract
Background
Propofol is an intravenous sedative hypnotic agent widely used for induction and maintenance
of general anesthesia. Pain is an acknowledged reaction of propofol administration which can
be very disquieting to the patient [1–3]. Identifying an ideal method to lower the pain levels
precipitated by propofol on induction has been a challenge and thus several studies have been
conducted in view of the same, one being the use of lignocaine with venous occlusion [4].
Study Objective
To compare the two methods used to reduce propofol-induced pain; one involving venoocclusion with lignocaine and one using lignocaine without veno-occlusion during Propofol
injection.
Study Design
This was a comparative observational study carried out at the KNH main theatre during
induction of anesthesia. 78 adult patients aged between 18-85 years were included in this study.
The study procedure was explained to eligible patients and a written informed consent
obtained. The anesthetic choice and application was at the discretion of the attending
anesthesiologist to whom information was made known that observation would be made using
VAS scores on tolerability to pain with propofol administration.
Results
lidocaine is widely used for alleviating PVP and our findings showed that giving 40mg of 2%
lidocaine for 60seconds with venous occlusion [4–6] has proven to be more superior and
effective than giving lidocaine alone prior to propofol administration with no major correlation
on age, gender or ASA status. This is confirmed from the lower mean pain scores in the veno
occlusion group compared to the lidocaine alone group. (U=110, P= <0.001)
Conclusion
It is apparent that the strategy to preclude PVP should be multifaceted and that giving 40mg of
2% lidocaine for 60seconds with venous occlusion [4–6] has proven to be more superior and
effective than giving lidocaine alone prior to propofol administration.
Publisher
University of Nairobi
Rights
Attribution-NonCommercial-NoDerivs 3.0 United StatesUsage Rights
http://creativecommons.org/licenses/by-nc-nd/3.0/us/Collections
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