Pharmacological activities of pistia stratiotes
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Date
1997Author
Munenge, Rahab W.
Achola, K. J.
Indalo, A. A.
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
The pharmacologic activities of Pistia stratiotes were studied. Calcium channel blocking activity of a methanol extract of the whole plant was demonstrated using isolated segments of rabbit jejunum and confirmed via inhibition by pretreatment with verapamil. Additionally, the plant extract exhibited dose-related bronchodilating activity on isolated guinea pig trachea and neuromuscular blocking action, which was also dose-related. The plant extract caused a decrease in blood pressure in anaesthetised rats. After a 10 μg dose of the extract, systolic and diastolic blood pressures fell by 18% and 10%, respectively. Further doses of the plant extract produced slight decreases in blood pressures in anaesthetised rats. The systolic, diastolic and mean blood pressures before the extract were all significantly higher (P < 0.001) than those following the administration of the extract
URI
http://informahealthcare.com/doi/abs/10.1080/09251619708951277?journalCode=phbhttp://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/16094
Citation
Pharmaceutical BiologyPublisher
Departmnent of Medicine, College of Health Sciences, University of Nairobi
Collections
- Faculty of Health Sciences (FHS) [10378]