| dc.contributor.author | Munenge, Rahab W. | |
| dc.contributor.author | Achola, K. J. | |
| dc.contributor.author | Indalo, A. A. | |
| dc.date.accessioned | 2013-04-16T08:31:53Z | |
| dc.date.available | 2013-04-16T08:31:53Z | |
| dc.date.issued | 1997 | |
| dc.identifier.citation | Pharmaceutical Biology | en |
| dc.identifier.uri | http://informahealthcare.com/doi/abs/10.1080/09251619708951277?journalCode=phb | |
| dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/16094 | |
| dc.description.abstract | The pharmacologic activities of Pistia stratiotes were studied. Calcium channel blocking activity of a methanol extract of the whole plant was demonstrated using isolated segments of rabbit jejunum and confirmed via inhibition by pretreatment with verapamil. Additionally, the plant extract exhibited dose-related bronchodilating activity on isolated guinea pig trachea and neuromuscular blocking action, which was also dose-related. The plant extract caused a decrease in blood pressure in anaesthetised rats. After a 10 μg dose of the extract, systolic and diastolic blood pressures fell by 18% and 10%, respectively. Further doses of the plant extract produced slight decreases in blood pressures in anaesthetised rats. The systolic, diastolic and mean blood pressures before the extract were all significantly higher (P < 0.001) than those following the administration of the extract | en |
| dc.language.iso | en | en |
| dc.relation.ispartofseries | Vol. 35, No. 5 , Pages 329-333 (1997); | |
| dc.title | Pharmacological activities of pistia stratiotes | en |
| dc.type | Article | en |
| local.publisher | Departmnent of Medicine, College of Health Sciences, University of Nairobi | en |
