Outdoor malaria vector species profile in dryland ecosystems of Kenya
View/ Open
Date
2022-05Author
Kinya, Fiona
Mutero, Clifford M
Sang, Rosemary
Owino, Eunice A
Rotich, Gilbert
Ogola, Edwin O
Wondji, Charles S
Torto, Baldwyn
Tchouassi, David P
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Outdoor biting by anopheline mosquitoes is one of the contributors to residual malaria transmission, but the profile of vectors driving this phenomenon is not well understood. Here, we studied the bionomics and genetically characterized populations of An. gambiae and An. funestus complexes trapped outdoors in three selected dryland areas including Kerio Valley, Nguruman and Rabai in Kenya. We observed a higher abundance of Anopheles funestus group members (n = 639, 90.6%) compared to those of the An. gambiae complex (n = 66, 9.4%) with An. longipalpis C as the dominant vector species with a Plasmodium falciparum sporozoite rate (Pfsp) of 5.2% (19/362). The known malaria vectors including An. funestus s.s. (8.7%, 2/23), An. gambiae (14.3%, 2/14), An. rivulorum (14.1%, 9/64), An. arabiensis (1.9%, 1/52) occurred in low densities and displayed high Pfsp rates, which varied with the site. Additionally, six cryptic species found associated with the An. funestus group harbored Pf sporozoites (cumulative Pfsp rate = 7.2%, 13/181). We detected low frequency of resistant 119F-GSTe2 alleles in An. funestus s.s. (15.6%) and An. longipalpis C (3.1%) in Kerio Valley only. Evidence of outdoor activity, emergence of novel and divergent vectors and detection of mutations conferring metabolic resistance to pyrethroid/DDT could contribute to residual malaria transmission posing a threat to effective malaria control.
Citation
Kinya F, Mutero CM, Sang R, Owino EA, Rotich G, Ogola EO, Wondji CS, Torto B, Tchouassi DP. Outdoor malaria vector species profile in dryland ecosystems of Kenya. Sci Rep. 2022 May 3;12(1):7131. doi: 10.1038/s41598-022-11333-2. PMID: 35505087; PMCID: PMC9065082.Publisher
University of Nairobi
Rights
Attribution-NonCommercial-NoDerivs 3.0 United StatesUsage Rights
http://creativecommons.org/licenses/by-nc-nd/3.0/us/Collections
- Faculty of Health Sciences (FHS) [10378]
The following license files are associated with this item: