dc.contributor.author | Macdonald, K S | |
dc.contributor.author | Malonza, I | |
dc.contributor.author | Chen, D K | |
dc.contributor.author | Nagelkerke, N J | |
dc.contributor.author | Nasio, J M | |
dc.contributor.author | Ndinya-Achola, JO | |
dc.contributor.author | Bwayo, JJ | |
dc.contributor.author | Sitar, D S | |
dc.contributor.author | Aoki, F Y | |
dc.date.accessioned | 2013-05-31T12:09:53Z | |
dc.date.available | 2013-05-31T12:09:53Z | |
dc.date.issued | 2001-03-30 | |
dc.identifier.citation | Macdonald Ks, Malonza I, Chen Dk, Nagelkerke Nj, Nasio Jm, Ndinya-achola J, Bwayo Jj, Sitar Ds, Aoki Fy, Plummer Fa.vitamin A And Risk Of Hiv-1 Seroconversion Among Kenyan Men With Genital Ulcers.aids. 2001 Mar 30;15(5):635-9., O., Prof. Ndinya-achola J. , Aids. 2001 Mar 30;15(5):635-9., (2001) | en |
dc.identifier.uri | Http://profiles.uonbi.ac.ke/jndinya/publications/macdonald-ks-malonza-i-chen-dk-nagelkerke-nj-nasio-jm-ndinya-achola-j-bwayo-jj- | |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/28347 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pubmed/11317002. | |
dc.description.abstract | Background: Vitamin A is involved in normal immune function and the maintenance of mucosal integrity through complex effects on cellular differentiation. Objective: We sought to determine whether serum vitamin A levels were associated with altered susceptibility to primary infection with HIV-1 in men with high-risk sexual behaviour and genital ulcers who presented for treatment at an STD clinic in Nairobi, Kenya. Methods: HIV-1 seronegative men were prospectively followed. Vitamin A levels at study entry were compared among 38 men who HIV-1 seroconverted versus 94 controls who remained HIV seronegative. Results: Vitamin A deficiency (retinol less than 20 microg/dl) was very common and was present in 50% of HIV-1 seroconverters versus 76% of persistent seronegatives. Seroconversion was independently associated with a retinol level greater than 20 microg/dl (HR 2.43, 95% CI 1.25-4.70 | en |
dc.language.iso | en | en |
dc.publisher | University of Nairobi | en |
dc.title | Vitamin A And Risk Of HIV-1 Seroconversion Among Kenyan Men With Genital Ulcers. | en |
dc.type | Article | en |
local.publisher | School of Public Health Centre for HIV Prevention and Research | en |