dc.contributor.author | Hawken, MP | |
dc.contributor.author | Ojoo, JC | |
dc.contributor.author | Morris, JS | |
dc.contributor.author | Kariuki, EW | |
dc.contributor.author | Githui, WA | |
dc.contributor.author | Juma, ES | |
dc.contributor.author | Gathua, SN | |
dc.contributor.author | Kimari, JN | |
dc.contributor.author | Thiong'o, LN | |
dc.contributor.author | Raynes, JG | |
dc.contributor.author | Broadbent, P | |
dc.contributor.author | Gilks, CF | |
dc.contributor.author | Otieno, LS | |
dc.contributor.author | McAdam, KP | |
dc.date.accessioned | 2013-06-06T13:31:53Z | |
dc.date.available | 2013-06-06T13:31:53Z | |
dc.date.issued | 1996 | |
dc.identifier.citation | Clinical Research Centre, Kenya Medical Research Institute, Nairobi, Kenya. Tuber Lung Dis. 1996 Oct;77(5):444-8. | en |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pubmed/8959149 | |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/29354 | |
dc.description.abstract | SETTING:
Acute medical wards, Kenyatta National Hospital, Nairobi, Kenya.
OBJECTIVE:
To determine the prevalence of adrenocortical insufficiency in human immunodeficiency virus (HIV)-1 infected and non-infected patients with tuberculosis.
DESIGN:
One hundred and seventy-four patients with proven tuberculosis (90 HIV-1 positive and 84 HIV-1 negative) were assessed for adrenocortical insufficiency with a 30 min synacthen stimulation test.
RESULTS:
Fifty-one percent of those with pulmonary tuberculosis and 56% of those with extra-pulmonary tuberculosis had a subnormal cortisol response. However there was no statistically significant difference between the HIV-1 infected and non-infected patients in either group.
CONCLUSION:
While an impaired cortisol response is common in tuberculosis, it is no more prevalent in HIV-1 infected patients than non-infected patients with tuberculosis. | en |
dc.language.iso | en | en |
dc.title | No increased prevalence of adrenocortical insufficiency in human immunodeficiency virus-associated tuberculosis. | en |
dc.type | Article | en |
local.publisher | Medicine, University of Nairobi, | en |