dc.contributor.author | Nyindo, M | |
dc.contributor.author | Borus, P K | |
dc.contributor.author | Farah, I O | |
dc.contributor.author | Oguya, F O | |
dc.contributor.author | Makawiti, D W | |
dc.date.accessioned | 2013-06-10T07:27:14Z | |
dc.date.available | 2013-06-10T07:27:14Z | |
dc.date.issued | 1995 | |
dc.identifier.citation | Schistosoma mansoni in the baboon: modulation of pathology after vaccination with polyclonal anti-idiotypic antibodies. Nyindo M, Borus PK, Farah IO, Oguya FO, Makawiti DW. Scand J Immunol. 1995 Dec;42(6):637-43. | en |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pubmed/8552987 | |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/30428 | |
dc.description.abstract | Vaccination of five baboons with an anti-idiotypic vaccine to irradiated Schistosoma mansoni cercariae resulted in nearly 19% protection compared to 39% protection conferred to five baboons vaccinated with an irradiated vaccine. Vaccination with the anti-idiotypic antibodies resulted in a significant reduction of pathology and granuloma size following challenge with live unattenuated cercariae. Results presented in this work are considered highly significant because the anti-idiotypic vaccine markedly influenced schistosomiasis morbidity which is the main consideration in this disease. | en |
dc.language.iso | en | en |
dc.title | Schistosoma mansoni in the baboon: modulation of pathology after vaccination with polyclonal anti-idiotypic antibodies. | en |
dc.type | Article | en |
local.publisher | Parasitology, National Museums of Kenya, Nairobi, Kenya. | en |