| dc.contributor.author | Kidokoro, K | |
| dc.contributor.author | Ito, K | |
| dc.contributor.author | Ogoyi, DO | |
| dc.contributor.author | Abe, H | |
| dc.contributor.author | Mita, K | |
| dc.contributor.author | Kadono-Okuda, K | |
| dc.date.accessioned | 2013-06-10T10:01:08Z | |
| dc.date.available | 2013-06-10T10:01:08Z | |
| dc.date.issued | 2010 | |
| dc.identifier.citation | J Invertebr Pathol. 2010 Jan;103(1):79-81 | en |
| dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pubmed/19836396 | |
| dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/30635 | |
| dc.description.abstract | In the silkworm Bombyx mori, densovirus type 1 (BmDNV-1) replicates only in the midgut and causes fatal disease. Resistance to BmDNV-1 is determined by two genes, nsd-1 and Nid-1, respectively. Neither of them has been identified yet. We investigated the viral transcript by RT-PCR in inoculated silkworms carrying different sets of nsd-1 and Nid-1 genotype. BmDNV-1 transcript was not detected in nsd-1-carrying strains irrespective of existence of Nid-1 but clearly detected in strains carrying Nid-1 without nsd-1. The result suggests that nsd-1 blocks early step of infection. On the other hand, Nid-1 does not block cell and nucleus entry and viral transcription in nuclei but blocks later step in the viral infection cycle | en |
| dc.language.iso | en | en |
| dc.title | Non-susceptibility genes to Bombyx densovirus type 1, Nid-1 and nsd-1, affect distinct steps of the viral infection pathway | en |
| dc.type | Article | en |
| local.publisher | Division of Insect Sciences, National Institute of Agrobiological Sciences, Tsukuba, Ibaraki, Japan | en |
| local.publisher | Department of Medicine, University of Nairobi | en |
