Therapeutic potential of folate uptake inhibition in Plasmodium falciparum

dc.contributor.advisor
dc.contributor.author	Nzila, AM
dc.contributor.author	Kokwaro, G
dc.contributor.author	Winstanley, PA
dc.contributor.author	Marsh, K
dc.contributor.author	Ward, SA
dc.date.accessioned	2013-06-10T12:36:12Z
dc.date.available	2013-06-10T12:36:12Z
dc.date.issued	2004
dc.identifier.citation	Trends Parasitol. 2004 Mar;20(3):109-12	en
dc.identifier.uri	http://www.ncbi.nlm.nih.gov/pubmed/16676416
dc.identifier.uri	http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/30815
dc.description.abstract	Plasmodium falciparum parasites resistant to the combination sulfadoxine-pyrimethamine are spreading in Africa, particularly in East Africa. This is a matter of concern because there are no other affordable drugs available. This article provides the evidence indicating that sulfadoxine-pyrimethamine resistance can be reversed in vitro and discusses how this information might be exploited to extend the therapeutic lifetime of sulfadoxine-pyrimethamine in vivo	en
dc.language.iso	en	en
dc.publisher	University of Nairobi	en
dc.title	Therapeutic potential of folate uptake inhibition in Plasmodium falciparum	en
dc.type	Article	en
local.publisher	College of Humanities Sciences	en