| dc.contributor.author | Mukiibi, JM | |
| dc.contributor.author | Paul, B | |
| dc.date.accessioned | 2013-06-10T15:35:21Z | |
| dc.date.available | 2013-06-10T15:35:21Z | |
| dc.date.issued | 1994 | |
| dc.identifier.citation | Trop Geogr Med. 1994;46(1):17-9. | en |
| dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pubmed/8165730 | |
| dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/31072 | |
| dc.description.abstract | Forty two patients who were seen and satisfied the French-American-British (FAB) diagnostic criteria for myelodysplastic syndromes (MDS) over a 6-year period at the University of Zimbabwe's Department of Haematology, Harare, are presented. Their overall ages ranged from 29 to 75 years with a mean +/- SD of 57.8 +/- 11.2 years. Males outnumbered females with a male to female ratio of 1.2:1. Refractory anaemia (RA) occurred in 33.3%; refractory anaemia with ringed sideroblasts (RARS) in 16.7%; refractory anaemia with excess blasts (RAEB) in 21.4%; refractory anaemia with excess blasts in transformation (RAEB-T) in 16.7% and chronic myelomonocytic leukaemia (CMML) in 11.9% of the patients. In 90.5% the disease was primary and in 9.5% prior exposure to myelotoxic agents resulted in secondary MDS. The study reveals that MDS as a cause of anaemia in the African population is usually hidden in the big number of well known anaemias due to rampant malaria, malnutrition and a host of nutritional deficiencies. There is therefore the need to increase diagnostic awareness among our clinicians about the existence of these disorders | en |
| dc.language.iso | en | en |
| dc.publisher | University of Nairobi | en |
| dc.title | Myelodysplastic syndromes (MDS) in Central Africans | en |
| dc.type | Article | en |
| local.publisher | Department of Haematology and Blood Transfusion | en |
