dc.contributor.author | Turner, DA | |
dc.contributor.author | Shribman, AJ | |
dc.contributor.author | Smith, G | |
dc.contributor.author | Achola, KJ | |
dc.date.accessioned | 2013-06-12T08:42:32Z | |
dc.date.available | 2013-06-12T08:42:32Z | |
dc.date.issued | 1986-12 | |
dc.identifier.citation | Br J Anaesth. 1986 Dec;58(12):1365-70. | en |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pubmed/3790388 | |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/32057 | |
dc.description.abstract | The catecholamine and cardiovascular responses to intubation were investigated during halothane anaesthesia. Thirty patients were allocated randomly to two groups. Following induction of anaesthesia and muscle relaxation, group 1 was ventilated with 70% nitrous oxide in oxygen before intubation; group 2 received 1% halothane in addition. After intubation, both groups received 0.5% halothane. Arterial pressure and heart rate, and plasma noradrenaline and adrenaline concentrations were measured throughout the induction sequence. In group 1 intubation was associated with increases (from pre-induction values) in systolic arterial pressure of 13% and diastolic arterial pressure of 35%, although the plasma concentrations of noradrenaline did not alter significantly. In group 2, although there was a pressor response to intubation, no overall change in systolic arterial pressure and only a 13% increase in diastolic arterial pressure occurred when compared with pre-induction values. This response was associated with a 78% increase in the noradrenaline concentration; the adrenaline concentration did not alter significantly. | en |
dc.language.iso | en | en |
dc.publisher | University of Nairobi, | en |
dc.title | Effect of halothane on cardiovascular and plasma catecholamine responses to tracheal intubation | en |
dc.type | Article | en |
local.publisher | School of Medicine, University of Nairobi | en |