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Traumatic endophthalmitis presenting as isolated retinal vasculitis and white-centered hemorrhages: Case report and review of literature
(University of Nairobi, 2012-07)
The article reports a case and review of the literature of endophthalmitis presenting as isolated retinal vasculitis. A 26-year-old male was observed to have white-centered retinal hemorrhages and retinal vasculitis following ...
Long-term Virologic Response and Genotypic Resistance Mutations in HIV-1 Infected Kenyan Children on Combination Antiretroviral Therapy.
(University of Nairobi., 2012-11-28)
Backround: HIV-infected children may require the use of combination antiretroviral treatment (cART) into adulthood. However, regimens are limited to first- and second-line in many African settings. Therefore, understanding ...
Local perceptions of intermittent screening and treatment for malaria in school children on the south coast of Kenya.
(University of Nairobi, 2012)
BACKGROUND:
The intermittent screening and treatment (IST) of school children for malaria is one possible intervention strategy that could help reduce the burden of malaria among school children. Future implementation ...
OSI-930 analogues as novel reversal agents for ABCG2-mediated multidrug resistance
(2012)
OSI-930, a dual c-Kit and KDR tyrosine kinase inhibitor, is reported to have undergone a Phase I dose escalation study in patients with advanced solid tumors. A series of fifteen pyridyl and phenyl analogues of OSI-930 ...
Consistency of Mycobacterium tuberculosis-specific interferon-gamma responses in HIV-1-infected women during pregnancy and postpartum.
(University of Nairobi., 2012)
Background: We determined the consistency of positive interferon-gamma (IFN-γ) release assays (IGRAs) to detect latent TB infection (LTBI) over one-year postpartum in HIV-1-infected women. Methods: Women with positive IGRAs ...
Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis
(2012)
Abstract
Aging is characterized by clonal expansion of myeloid-biased hematopoietic stem cells and by increased risk of myeloid malignancies. Exome sequencing of three elderly females with clonal hematopoiesis, demonstrated ...
What determines membership to farmer groups in Uganda: Evidence from the Uganda Census of Agriculture 2008/09
(2012-05)
Farmer groups have returned to the policy agenda of many developing countries because of
their attractiveness as facilitators and accelerators of technical and economic change in rural
areas and as potential avenues for ...
Prinzmetal's Angina in a Pregnant Woman: a Case Report.
(University of Nairobi, 2012)
Acute myocardial infarction (MI) during pregnancy is rare and MI due to Prinzmetal's angina is much rarer. We present a 35-year-old, obese, multigravida, and pre-eclamptic woman, who developed acute anterior wall MI at the ...
Antiparasitic and anticancer carvotacetone derivatives of Sphaeranthus bullatus.
(University of Nairobi, 2012-09)
The CH2Cl2-MeOH (1:1) extract of the aerial parts of Sphaeranthus bullatus, an annual herb native to tropical East Africa, showed activity against chloroquine sensitive D6 (IC50 9.7 microg/mL) and chloroquine resistant W2 ...
Association between participant self-report and biological outcomes used to measure sexual risk behavior in HIV-1- seropositive female sex workers in Mombasa, Kenya
(2012)
Few studies have examined the association between self-reported sexual risk behaviors and biologic outcomes in human immunodeficiency virus (HIV)-1-seropositive African adults.
METHODS:
We conducted a prospective cohort ...