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The effect of treatment of schistosomiasis on blood plasma HIV-1 RNA concentration in coinfected individuals.
(University of Nairobi, 2000)
Abstract
OBJECTIVE:
To determine whether drug treatment of Schistosomiasis mansoni infection leads to a reduction in plasma HIV-1 RNA concentration in coinfected individuals.
METHODS:
Stool and plasma samples were ...
Correlation between eosinophils and protection against reinfection with Schistosoma mansoni and the effect of human immunodeficiency virus type 1 coinfection in humans.
(University of Nairobi, 2006-04)
Longitudinal investigations of an adult male population of Kenyan car washers who have heavy and quantifiable occupational exposure to Schistosoma mansoni cercariae revealed that some individuals develop resistance to ...
T regulatory cell levels decrease in people infected with Schistosoma mansoni on effective treatment.
(University of Nairobi, 2007-10)
Schistosomiasis mansoni is usually a chronic infection that leads to long-term, systemic exposure to schistosome antigens. Experimental Schistosoma mansoni infection is associated with immunoregulatory mechanisms, including ...
Higher percentages of circulating mast cell precursors correlate with susceptibility to reinfection with Schistosoma mansoni.
(University of Nairobi, 2006-12)
A high level of serum IgE is generally associated with human resistance to schistosomes, though the protective mechanisms of IgE remain undefined. We recently reported that whereas some individuals who are occupationally ...
Short report: Evaluation of hepatic fibrosis in persons co-infected with Schistosoma mansoni and human immunodeficiency virus 1. , ,, , , .
(University of Nairobi, 2004)
Abstract
To investigate whether infection with human immunodeficiency virus 1 (HIV-1) affects fibrosis development in patients infected with Schistosoma mansoni, we evaluated schistosomiasis-induced pathology in the ...
Geographic distribution of schistosomiasis and soil-transmitted helminths in Western Kenya: implications for anthelminthic mass treatment., , , , , ,.
(University of Nairobi, 2003)
Abstract
A survey of 1,246 children 10-12 years old in 32 primary schools in Kenya near Lake Victoria was conducted to determine prevalence and distribution of schistosome and geohelminth infections. Stool and urine ...
Interactions between schistosomiasis and human immunodeficiency virus in Western Kenya
(University of Nairobi, 2004)
Abstract
For the past ten years, we have been exploring the relationship between schistosomiasis and human immunodeficiency virus (HIV-1) and how coinfection with both agents may affect the pathology and progression of ...
A five-country evaluation of a point-of-care circulating cathodic antigen urine assay for the prevalence of Schistosoma mansoni.
(University of Nairobi., 2013-03)
We evaluated a commercial point-of-care circulating cathodic antigen (POC-CCA) test for assessing Schistosoma mansoni infection prevalence in areas at risk. Overall, 4,405 school-age children in Cameroon, Côte d'Ivoire, ...
Effect of four rounds of annual school-wide mass praziquantel treatment for schistosoma mansoni control on schistosome-specific immune responses.
(University of Nairobi, 2018)
This study evaluated potential changes in antischistosome immune responses in chil-dren from schools that received 4 rounds of annual mass drug administration (MDA) of praziquantel (PZQ). In a repeated cross-sectional study ...
Association of the gene polymorphisms IFN-gamma +874, IL-13 -1055 and IL-4 -590 with patterns of reinfection with Schistosoma mansoni.
(University of Nairobi, 2009)
BACKGROUND:
The immunologic findings that most consistently correlate with resistance in human schistosomiasis are high levels of IgE and low levels of IgG4. We have genotyped gene and promoter polymorphisms of cytokines ...