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Evaluation of performance of the Gen-Probe human immunodeficiency virus type 1 viral load assay using primary subtype A, C, and D isolates from Kenya.
(University of Nairobi, 2000-07)
Accurate and sensitive quantification of human immunodeficiency virus type 1 (HIV-1) RNA has been invaluable as a marker for disease prognosis and for clinical monitoring of HIV-1 disease. The first generation of commercially ...
Micronutrient supplementation increases genital tract shedding of HIV-1 in women: results of a randomized trial
(2004)
To test the hypothesis that micronutrient supplementation decreases genital HIV-1 shedding, a double-blind, randomized, placebo-controlled trial of 6 weeks of multivitamin plus selenium supplementation vs. placebo was ...
Genital shedding of human immunodeficiency virus type 1 DNA during pregnancy: association with immunosuppression, abnormal cervical or vaginal discharge, and severe vitamin A deficiency
(1997-01)
The presence of human immunodeficiency virus type 1 (HIV-1) in genital secretions may be a determinant of vertical HIV-1 transmission. Cervical and vaginal secretions from HIV-1–seropositive pregnant women were evaluated ...
Cervical and vaginal shedding of human immunodeficiency virus type 1-infected cells throughout the menstrual cycle
(University of Nairobi, 1998-10)
Cervical and vaginal secretions from 17 women infected with human immunodeficiency virus type 1 (HIV-1) were evaluated daily through the course of one menstrual cycle for HIV-1 DNA (21-31 visits per woman). HIV-1-infected ...
Hormonal contraception, vitamin A deficiency, and other risk factors for shedding of HIV-1 infected cells from the cervix and vagina.
(University of Nairobi, 1997-09)
BACKGROUND: Factors that influence shedding of HIV-1 infected cells in cervical and vaginal secretions may be important determinants of sexual and vertical transmission of the virus. We investigated whether hormonal ...
Association Between Cervical Shedding Of Herpes Simplex Virus And Hiv-1.aids
(University of Nairobi, 2002-12-06)
OBJECTIVE: To investigate the association between the cervical shedding of herpes simplex virus (HSV) and HIV-1. DESIGN: A cross-sectional study on 200 women seropositive for both HSV-2 and HIV-1 was conducted in a family ...
Cervical Shedding Of Cytomegalovirus In Human Immunodeficiency Virus Type 1-infected Women.
(University of Nairobi, 1999)
Cervical shedding of cytomegalovirus (CMV) is important in transmission of CMV to exposed sexual partners and neonates. We evaluated prevalence and correlates of CMV DNA shedding in cervical secretions from a large cohort ...
Selenium deficiency is associated with shedding of HIV-1--infected cells in the female genital tract.
(2001)
Objective: To assess the relation between selenium deficiency and vaginal or cervical shedding of HIV-1-infected cells.
Design: Cross-sectional study of 318 HIV-1 seropositive women in Mombasa, Kenya.
Methods: Vaginal ...
Vitamin A supplementation and human immunodeficiency virus type 1 shedding in women: results of a randomized clinical trial.
(2002)
Observational studies have associated vitamin A deficiency with vaginal shedding of human immunodeficiency virus (HIV) type 1-infected cells and mother-to-child HIV-1 transmission. To assess the effect of vitamin A ...
Phylogenetic evaluation of Kenyan HIV type 1 isolates.AIDS Res Hum Retroviruses
(University of Nairobi, 1997-04)
Diversity among global isolates of HIV-1 presents a formidable challenge for vaccine development. As distinct clades of the virus are recognized, it will be important to monitor their geographic distribution and divergence. ...