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Validity of the vaginal discharge algorithm among pregnant and non-pregnant women in Nairobi, Kenya
(University of Nairobi., 2000-02)
OBJECTIVE:
To evaluate the validity of different algorithms for the diagnosis of gonococcal and chlamydial infections among pregnant and non-pregnant women consulting health services for vaginal discharge in Nairobi, ...
A simple and quick method for enhanced detection of specific IgE in serum from lymphatic filariasis patients
(2001)
A new simple and quick technique, using a suspension of protein A agarose beads to absorb IgG4 from sera prior
to determination of filarial-specific IgE in ELISA, is presented. The optimal ratio between serum and absorbant ...
Filarial-specific antibody response in East African bancroftian filariasis
(2006)
The effect of host infection, chronic clinical disease, and transmission intensity on the patterns of specific
antibody responses in Bancroftian filariasis was assessed by analyzing specific IgG1, IgG2, IgG3, IgG4, and ...
Transmission intensity and the immunoepidemiology of bancroftian filariasis in East Africa
(2001)
Previous attempts to determine the interactions between filariasis transmission intensity, infection and chronic disease have been limited by a lack of a theoretical framework that allows the explicit examination of ...
The effect of eight half-yearly single-dose treatments with DEC on Wuchereria bancrofti circulating antigenaemia
(2005)
The effect of eight half-yearly treatment rounds with diethylcarbamazine
(DEC; 6 mg/kg bodyweight) on Wuchereria bancrofti-specific circulating
filarial antigen (CFA), a marker of adult worm infection, was followed in ...
Wuchereria bancrofti in a community with seasonal transmission: stability of microfilaraemia, antigenaemia and filarial-specific antibody concentrations.
(2001)
The effect of seasonal transmission on microfilaraemia, antigenaemia and filarial-specific antibody levels in individuals infected with Wuchereria bancrofti was investigated in a follow-up study in an endemic community in ...
HIV-1 subtype D infection is associated with faster disease progression than subtype A in spite of similar plasma HIV-1 Loads
(2007)
We investigated the effect of human immunodeficiency virus
type 1 (HIV-1) subtype on disease progression among 145
Kenyan women followed from the time of HIV-1 acquisition.
Compared with those infected with subtype A, ...
Bacterial vaginosis in HIV-infected women induces reversible alterations in the cervical immune environment
(2008)
Bacterial vaginosis (BV) has been associated with
increased HIV cervicovaginal shedding. We hypothesized that this might relate to BV-associated increases in mucosal activated CD4+ T cells, which could enhance local HIV ...
A Prospective study of vaginal bacterial flora and other risk factors for vulvovaginal candidiasis
(2009-06)
Background. It has been suggested that vaginal colonization with lactobacilli may reduce the risk of vulvovaginal
candidiasis (VVC), but supporting data are limited. Our objective was to determine the relationship between ...
Safety and immunogenicity of recombinant low-dosage HIV-1 A vaccine candidates vectored by plasmid pTHr DNA or modified vaccinia virus Ankara (MVA) in humans in East Africa
(2008)
Summary: The safety and immunogenicity of plasmid pTHr DNA, modified vaccinia virus Ankara
(MVA) human immunodeficiency virus type 1 (HIV-1) vaccine candidates were evaluated in four
Phase I clinical trials in Kenya and ...