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Latent tuberculosis detection by interferon γ release assay during pregnancy predicts active tuberculosis and mortality in human immunodeficiency virus type 1-infected women and their children.
(University of Nairobi., 2010-12)
BACKGROUND:
We evaluated the prognostic usefulness of interferon γ release assays (IGRAs) for active tuberculosis and mortality in Kenyan human immunodeficiency virus type 1 (HIV-1)-infected women and their infants.
ME ...
High uptake of postpartum hormonal contraception among HIV-1-seropositive women in Kenya.
(2007)
The objectives of this study were to determine patterns of contraceptive utilization among sexually active HIV-1-seropositive women postpartum and to identify correlates of hormonal contraception uptake.
The goal of this ...
Establishing and sustaining a healthy vaginal environment: analysis of data from a randomized trial of periodic presumptive treatment for vaginal infections
(2011)
Data from a randomized trial of oral periodic presumptive treatment (PPT) to reduce vaginal infections were analyzed to assess the effect of the intervention on a healthy vaginal environment (normal flora confirmed by Gram ...
Herpes simplex virus type 2 and risk of intrapartum human immunodeficiency virus transmission.
(2007)
OBJECTIVE:
To determine whether herpes simplex virus type 2 (HSV-2) infection was associated with risk of intrapartum human immunodeficiency virus type 1 (HIV-1) transmission and to define correlates of HSV-2 infection ...
Home visits during pregnancy enhance male partner HIV counselling and testing in Kenya: a randomized clinical trial.
(University of Nairobi, 2013-08)
BACKGROUND::
HIV testing male partners of pregnant women may decrease HIV transmission to women and promote uptake of prevention of mother-to-child HIV transmission (PMTCT) interventions. However, it has been difficult ...
The Afya Bora Consortium: an Africa-US partnership to train leaders in global health.
(University of Nairobi, 2011)
The Afya Bora Consortium is a partnership of 8 academic health institutions, 4 in Africa and 4 in the United States. The Consortium is developing a Global Health Leadership Fellowship for medical, nursing, and public health ...
HIV-neutralizing Activity Of Cationic Polypeptides In Cervicovaginal Secretions Of Women In Hiv-serodiscordant Relationships.
(University of Nairobi, 2012)
BACKGROUND:
HIV exposed seronegative (HESN) women represent the population most in need of a prophylactic antiviral strategy. Mucosal cationic polypeptides can potentially be regulated for this purpose and we here aimed ...
Longitudinal assessment of human immunodeficiency virus type 1 (HIV-1)-specific gamma interferon responses during the first year of life in HIV-1-infected infants.
(University of Nairobi., 2005-07)
Human immunodeficiency virus type 1 (HIV-1) infection results in different patterns of viral replication in pediatric compared to adult populations. The role of early HIV-1-specific responses in viral control has not been ...
Delayed initiation of antiretroviral therapy among HIV-discordant couples in Kenya.
(2013)
Timely initiation of antiretroviral therapy (ART) is particularly important for HIV-discordant couples because viral suppression greatly reduces the risk of transmission to the uninfected partner. To identify issues and ...
Longitudinal comparison of chemokines in breastmilk early postpartum among HIV-1-infected and uninfected Kenyan women
(University of Nairobi., 2007-09)
Breastmilk chemokines have been associated with increased HIV-1 RNA levels in breastmilk and altered risk of mother-to-child HIV-1 transmission. To characterize CC and CXC chemokines in breastmilk postpartum, we collected ...