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Now showing items 11-20 of 22
Risk factors for postnatal mother-child transmission of HIV-1.
(2000)
OBJECTIVE:
To identify factors affecting HIV-1 breastfeeding transmission.
DESIGN:
Longitudinal observational cohort study.
METHODS:
HIV-1 seropositive pregnant women and seronegative controls were enrolled ...
A randomized, placebo-controlled trial of monthly azithromycin prophylaxis to prevent sexually transmitted infections and HIV-1 in Kenyan sex workers: study design and baseline findings
(2000)
Our objectives were to describe the baseline findings of a trial of antibiotic prophylaxis to prevent sexually transmitted infections (STIs) and HIV-1 in a cohort of Nairobi female sex workers (FSWs). A questionnaire was ...
Acute sexually transmitted infections increase human immunodeficiency virus type 1 plasma viremia, increase plasma type 2 cytokines, and decrease CD4 cell counts
(2000)
In Kenya, the median incubation time to AIDS in seroconverting sex workers is 4 years;
this incubation time is specific to female sex workers.We studied the influence of acute sexually transmitted infections (STIs) on ...
The female condom and STDs: design of a community intervention trial
(ScienceDirect, 2000)
OBJECTIVES: The main purpose of this study is to compare sexually transmitted disease (STD) prevalence in cohorts of women with and without access to female condoms.
METHODS: Six matched pairs of communities were ...
Mucosal and plasma IgA from HIV-1-exposed uninfected individuals inhibit HIV-1 523 transcytosis across human epithelial cells.
(2000)
Abstract
HIV-1-specific IgA has been described in the genital tract and plasma of HIV-1 highly exposed, persistently seronegative (HEPS) individuals, and IgA from these sites has been shown to neutralize HIV-1. This ...
Pattern Of Sexually Transmitted Diseases And Risk Factors Among Women Attending An Std Referral Clinic In Nairobi, Kenya
(University of Nairobi, 2000-08-27)
BACKGROUND: In Kenya, sexually transmitted disease (STD) clinics care for large numbers of patients with STD-related signs and symptoms. Yet, the etiologic fraction of the different STD pathogens remains to be determined, ...
Trends in HIV -1 Incidence in a Cohort of Prostitutes in Kenya: Implications for HIV -1 Vaccine Efficacy Trials
(2000)
Background: Accurate predictions of HIV-I incidence in potential study populations are essential for designing HIV-I vaccine efficacy trials. Lillie information is available on the estimated incidence of HIV-I in such ...
Baseline STD prevalence in a community intervention trial of the female condom in Kenya
(2000)
OBJECTIVE:
We present baseline sexually transmitted disease (STD) prevalence rates from an ongoing intervention trial at Kenyan agricultural sites.
METHODS:
After gaining the cooperation of management, we identified ...
Influence of HLA supertypes on susceptibility and resistance to human immunodeficiency virus type 1 infection.
(, 2000-05)
Certain human leukocyte antigens, by presenting conserved immunogenic epitopes for T cell recognition, may, in part, account for the observed differences in human immunodeficiency virus type 1 (HIV-1) susceptibility. To ...
HIV-1-specific mucosal CD8+ lymphocyte responses in the cervix of HIV-1-resistant prostitutes in Nairobi
(, 2000)
Understanding how individuals with a high degree of HIV exposure avoid persistent infection is paramount to HIV vaccine design. Evidence suggests that mucosal immunity, particularly virus-specific CTL, could be critically ...