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Now showing items 21-30 of 34
Higher set point plasma viral load and more-severe acute HIV type 1 (HIV-1) illness predict mortality among high-risk HIV-1-infected African women
(2006)
BACKGROUND:
There is limited information on the natural history of human immunodeficiency virus type 1 (HIV-1) infection in Africa, especially from individuals with well-defined dates of infection. We used data from a ...
Identification of modifiable factors that affect the genetic diversity of the transmitted HIV-1 population
(2004)
BACKGROUND:
Our previous studies have shown that the majority of African women were infected with multiple HIV-1 genetic variants, while in the remaining women only a single viral genotype was detected early in infection. ...
Vitamin A deficiency and the acute phase response among HIV-1-infected and -uninfected women in Kenya
(2002)
Among HIV-1-infected individuals, vitamin A deficiency has been associated with faster disease progression and greater infectivity in observational studies, but randomized clinical trials have shown no effect of vitamin A ...
Female-to-male infectivity of HIV-1 among circumcised and uncircumcised Kenyan men
(University of Nairobi,, 2005)
BACKGROUND:
A lack of male circumcision has been associated with increased risk of human immunodeficiency virus type 1 (HIV-1) acquisition in a number of studies, but questions remain as to whether confounding by behavioral ...
Relationship between markers of HIV-1 disease progression and serum beta-carotene concentrations in Kenyan women.
(University of Nairobi,, 2007)
Observational studies have suggested that low serum beta-carotene concentrations may influence HIV-1 disease progression. However, randomized trials have not demonstrated beneficial effects of beta-carotene supplementation. ...
Vitamin A supplementation and genital shedding of herpes simplex virus among HIV-1-infected women: a randomized clinical trial.
(University of Nairobi,, 2004)
Cross-sectional analyses have associated vitamin A deficiency with genital shedding of herpes simplex virus (HSV) among human immunodeficiency virus type 1 (HIV-1)-infected women. A randomized clinical trial of vitamin A ...
Trends in HIV -1 Incidence in a Cohort of Prostitutes in Kenya: Implications for HIV -1 Vaccine Efficacy Trials
(2000)
Background: Accurate predictions of HIV-I incidence in potential study populations are essential for designing HIV-I vaccine efficacy trials. Lillie information is available on the estimated incidence of HIV-I in such ...
HIV-1 infection alters the retinol-binding protein:transthyretin ratio even in the absence of the acute phase response.
(University of Nairobi,, 2005)
he ratio of retinol-binding protein (RBP) to transthyretin (TTR) has been proposed as an indirect method with which to assess vitamin A status in the context of inflammation. Few studies have been conducted among adults, ...
Hormonal Contraception And Risk Of Hiv-1 Acquisition: Results Of A 10-year Prospective Study.
(University of Nairobi, 2004-03-05)
A prospective study of risk factors for herpes simplex virus type 2 acquisition among high-risk HIV-1 seronegative women in Kenya
(2011)
OBJECTIVES:
Several studies have demonstrated an association between herpes simplex virus type 2 (HSV-2) and HIV-1, but available data on risk factors for HSV-2 acquisition are limited. The objective of this analysis ...