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Longitudinal comparison of chemokines in breastmilk early postpartum among HIV-1-infected and uninfected Kenyan women
(University of Nairobi., 2007-09)
Breastmilk chemokines have been associated with increased HIV-1 RNA levels in breastmilk and altered risk of mother-to-child HIV-1 transmission. To characterize CC and CXC chemokines in breastmilk postpartum, we collected ...
Triple-antiretroviral prophylaxis to prevent mother-to-child HIV transmission through breastfeeding--the Kisumu Breastfeeding Study, Kenya: a clinical trial.
(University of Nairobi., 2011-03)
BACKGROUND:
Effective strategies are needed for the prevention of mother-to-child HIV transmission (PMTCT) in resource-limited settings. The Kisumu Breastfeeding Study was a single-arm open label trial conducted between ...
Progress, challenges, and new opportunities for the prevention of mother-to-child transmission of HIV under the US President's Emergency Plan for AIDS Relief.
(2012)
In June 2011, the Joint United Nations Programme on HIV/AIDS, the US President's Emergency Plan for AIDS Relief (PEPFAR), and other collaborators outlined a transformative plan to virtually eliminate pediatric AIDS worldwide. ...
Preventing postnatal transmission of HIV-1 through breast-feeding: modifying infant feeding practices
(University of Nairobi., 2004-02)
Approaches to reducing or preventing the risk of postnatal transmission through breast-feeding include the avoidance of all breast-feeding and the use of exclusive replacement feeds or exclusive breast-feeding for a limited ...
Salivary human immunodeficiency virus (HIV)-1-specific immunoglobulin A in HIV-1-exposed infants in Kenya
(University of Nairobi., 2008-07)
Humoral immunity, and specifically immunoglobulin A (IgA) that is directed against human immunodeficiency virus (HIV)-1, may contribute to protection against HIV-1 acquisition at mucosal surfaces. HIV-1-specific IgA has ...
Breast-milk infectivity in human immunodeficiency virus type 1-infected mothers.
(University of Nairobi., 2003-03)
Human immunodeficiency virus type 1 (HIV-1) is transmitted through blood, genital secretions, and breast milk. The probability of heterosexual transmission of HIV-1 per sex act is.0003-.0015, but little is known regarding ...
Epidemic Meningococcal Disease In Nairobi, Kenya - 1989.
(University of Nairobi, 1989)
Division of Bacterial and Mycotic Diseases, Centers for Disease Control, Atlanta, GA 30333. An epidemic of meningococcal disease occurred in Nairobi, Kenya, during 1989, outside the "meningitis belt" of sub-Saharan Africa. ...
High maternal HIV-1 viral load during pregnancy is associated with reduced placental transfer of measles IgG antibody.
(University of Nairobi., 2005-12)
BACKGROUND:
Studies among HIV-1-infected women have demonstrated reduced placental transfer of IgG antibodies against measles and other pathogens. As a result, infants born to women with HIV-1 infection may not acquire ...
Optimizing paediatric HIV care in Kenya: challenges in early infant diagnosis
(University of Nairobi., 2008-02)
PROBLEM:
In 2003, the goal of the Kenyan Ministry of Health was to avail antiretroviral treatment (ART) to 50% of the estimated 250 000 eligible individuals by the end of 2005. By July 2005, 45 000 adults and more than ...
Acute HIV infection among Kenyan infants.
(University of Nairobi., 2008-01)
BACKGROUND:
Clinical signs and symptoms of acute human immunodeficiency virus (HIV) infection in infants are not well characterized.
METHODS:
Serial clinical assessments and HIV PCR assays were conducted in a cohort of ...