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Risk factors for postnatal mother-child transmission of HIV-1.
(2000)
OBJECTIVE:
To identify factors affecting HIV-1 breastfeeding transmission.
DESIGN:
Longitudinal observational cohort study.
METHODS:
HIV-1 seropositive pregnant women and seronegative controls were enrolled ...
Implementing voluntary medical male circumcision for HIV prevention in Nyanza Province, Kenya: lessons learned during the first year
(2011)
BACKGROUND:
In 2007, the World Health Organization endorsed male circumcision as an effective HIV prevention strategy. In 2008, the Government of Kenya (GoK) launched the national voluntary medical male circumcision ...
A prospective study of vaginal trichomoniasis and HIV-1 shedding in women on antiretroviral therapy
(2011-11-03)
Background
Trichomonas vaginalis has been associated with increased vaginal HIV-1 RNA shedding in antiretroviral therapy (ART)-naïve women. The effect of trichomoniasis on vaginal HIV-1 shedding in ART-treated ...
Identification of modifiable factors that affect the genetic diversity of the transmitted HIV-1 population
(2004)
BACKGROUND:
Our previous studies have shown that the majority of African women were infected with multiple HIV-1 genetic variants, while in the remaining women only a single viral genotype was detected early in infection. ...
Vitamin A deficiency and the acute phase response among HIV-1-infected and -uninfected women in Kenya
(2002)
Among HIV-1-infected individuals, vitamin A deficiency has been associated with faster disease progression and greater infectivity in observational studies, but randomized clinical trials have shown no effect of vitamin A ...
Pregnancy rates among female participants in phase I and phase IIA AIDS vaccine clinical trials in Kenya
(2009)
Female participants in AIDS candidate vaccine clinical trials must agree to use effective contraception to be enrolled into the studies, and for a specified period after vaccination, since the candidate vaccines’ effects ...
Vaginal Lavage With Chlorhexidine During Labour To Reduce Mother-to-child HIV Transmission: Clinical Trial In Mombasa, Kenya
(University of Nairobi, 2001-02)
OBJECTIVES: To evaluate the effect of vaginal lavage with diluted chlorhexidine on mother-to child transmission of HIV (MTCT) in a breastfeeding population. METHODS: This prospective clinical trial was conducted in a ...
Pattern Of Sexually Transmitted Diseases And Risk Factors Among Women Attending An Std Referral Clinic In Nairobi, Kenya
(University of Nairobi, 2000-08-27)
BACKGROUND: In Kenya, sexually transmitted disease (STD) clinics care for large numbers of patients with STD-related signs and symptoms. Yet, the etiologic fraction of the different STD pathogens remains to be determined, ...
Genital ulceration does not increase HIV-1 shedding in cervical or vaginal secretions of women taking antiretroviral therapy.
(University of Nairobi, 2011)
OBJECTIVES:
Genital ulcer disease (GUD) is associated with increased HIV-1-RNA shedding in antiretroviral therapy (ART)-naive women. The effect of GUD on HIV-1 shedding among ART-treated women is not known. The objective ...
Trends in HIV -1 Incidence in a Cohort of Prostitutes in Kenya: Implications for HIV -1 Vaccine Efficacy Trials
(2000)
Background: Accurate predictions of HIV-I incidence in potential study populations are essential for designing HIV-I vaccine efficacy trials. Lillie information is available on the estimated incidence of HIV-I in such ...