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Genomic selection using regularized linear regression models: ridge regression, lasso, elastic net and their extensions.
(University of Nairobi, 2012)
BACKGROUND:
Genomic selection (GS) is emerging as an efficient and cost-effective method for estimating breeding values using molecular markers distributed over the entire genome. In essence, it involves estimating the ...
Combinatorial prevention of HIV transmission in women: the case for a vaginal microbicide.
(University of Nairobi, 2011-07)
Women are now becoming pivotal in the epidemiological spread of HIV infection throughout the world, especially in developing countries, where heterosexual transmission accounts for more than 80% of all new HIV infections. ...
Inhibition of double-stranded RNA-dependent protein kinase strongly decreases cytokine production and release in peripheral blood mononuclear cells from patients with Alzheimer's disease.
(University of Nairobi, 2010)
Alzheimer's disease (AD), a neurodegenerative disorder, is the most common form of dementia in the elderly individuals. Among the pathogenic mechanisms in AD, chronic systemic inflammation is described and characterized ...
"Petrified ears" with idiopathic adult-onset pituitary insufficiency.
(University of Nairobi, 2012)
"Petrified ears" or calcification of auricular cartilage is an uncommonly reported condition. The most common causes of this phenomenon are local trauma, frost bite, and inflammation. Adrenal insufficiency is the most ...
Hydrologic Analysis For River Nyando Using SWAT
(University of Nairobi, 2011)
The Nyando River is one of the major Rivers in the Lake Victoria Basin. It drains parts
of Nandi, Kericho and Nyando districts. It has a catchment area of about 3600km−2
of Western Kenya and an average discharge of ...
Effect of rat serum lipoproteins on mRNA levels and amiodarone metabolism by cultured primary rat hepatocytes
(2013)
Hyperlipidemia can significantly increase amiodarone (AM) in vivo liver uptake and decrease its velocity of microsomal metabolism. Here, hepatocytes isolated from normolipidemic (NL) and hyperlipidemic rats were incubated ...
Neuronal hypertrophy and mast cells in histologically negative, clinically diagnosed acute appendicitis: a quantitative immunophenotypical analysis.
(University of Nairobi, 2010)
INTRODUCTION AND AIM:
In about 20-25% of appendicectomies performed for clinically suspected acute appendicitis, definite morphological changes are lacking on histopathological examination. The present study was done ...
Engineered reversal of drug resistance in cancer cells--metastases suppressor factors as change agents.
(University of Nairobi, 2013)
Building molecular correlates of drug resistance in cancer and exploiting them for therapeutic intervention remains a pressing clinical need. To identify factors that impact drug resistance herein we built a model that ...
Osteitis of the fourth metatarsal caused by a date palm thorn in a child: why the dorsum of the foot is the most commonly injured site.
(University of Nairobi, 2013-01)
The palms are frequent in the region of eastern Morocco. An insidious onset of a lytic lesion in the base of the fourth metatarsal caused by a date palm thorn in a 20-year-old patient is presented. An untreated embedded ...
Effect of Thidiazuron, NAA and BAP on in vitro propagation of Alstroemeria aurantiaca cv. Rosita from shoot tip explants
(University of Nairobi, 2010)
The objective of the study was to evaluate the potency of Thidiazuron (TDZ) as a
plant growth regulator when compared to combined auxin (NAA) and cytokinin
(BAP) in evoking morphogenic responses from Alstroemeria aurantiaca ...