Browsing Faculty of Science & Technology (FST) by Author "Tekwani BL."

Now showing items 1-3 of 3

    • Antimicrobial and antiparasitic abietane diterpenoids from the roots of Clerodendrum eriophyllum 

      Derese Solomon.; Machumi F.; Samoylenko V.; Yenesew Abiy.; Midiwo Jacob O.; Wiggers FT.; Jacob MR; Tekwani BL.; Khan SI.; Walker LA.; Muhammad I. (University of NairobiCollege of biological and physical science, 2010-06)
      Chromatographic separation of the roots of a Kenyan medicinal plant, Clerodendrum eriophyllum, led to the isolation of ten abietane diterpenoids (1-10), one of which (1) was isolated for the first time from a natural source. ...

    • Antiparasitic and anticancer carvotacetone derivatives from Sphaeranthus bullatus 

      Machumi F.; Yenesew Abiy.; Midiwo Jacob O.; Heydenreich M.; Kleinpeter E.; Khan S.; Tekwani BL.; Walker LA.; Muhammad I. (Department of Chemistry, University of NairobI, 2012-09)
      The 1:1 MeOH/CH2Cl2 extract of aerial parts of Sphaeranthus bullatus, an annual herb native to tropical East Africa, showed activity against chloroquine sensitive D6 (IC50 9.7µg/ml) and chloroquine resistant W2 (IC50 ...

    • Antiparasitic and antimicrobial isoflavanquinones from Abrus schimperi. 

      Rahman AA.; Samoylenko V.; Jain SK.; Tekwani BL.; Khan SI.; Jacob MR.; Midiwo Jacob O.; Hester JP.; Walker LA.; Muhammad I. (2011-11)
      The EtOH extract of Abrus schimperi (Fabaceae), collected in Kenya, demonstrated significant activity against Leishmania donovani promastigotes with IC50 value of 3.6 microg/mL. Bioassay-guided fractionation of CHCl3 ...