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Antiparasitic and anticancer carvotacetone derivatives of Sphaeranthus bullatus.
(University of Nairobi, 2012-09)
The CH2Cl2-MeOH (1:1) extract of the aerial parts of Sphaeranthus bullatus, an annual herb native to tropical East Africa, showed activity against chloroquine sensitive D6 (IC50 9.7 microg/mL) and chloroquine resistant W2 ...
Antibacterial activity and structure-activity relationships of a panel of 48 compounds from Kenyan plants against multidrug resistant phenotypes
(University of Nairobi, 2016)
In the current study forty eight compounds belonging to anthraquinones, naphthoquinones, benzoquinones, flavonoids (chalcones and polymethoxylated flavones) and diterpenoids (clerodanes and kauranes) were explored for their ...
Diterpenoid derivatives of Kenyan croton sylvaticus
(University of Nairobi, 2015)
Kenyan Croton sylvaticus Hochst. ex Krauss gave four clerodane diterpenoids, the new ent-3,13E-clerodadiene-15-formate (1), the known 15-acetoxy-ent-3,13E-clerodadiene (2), ent-3,13E-clerodadien-15-ol (3) and hardwickiic ...
Antiparasitic And Antimicrobial Constituents From Terminalia Brownii
(University of Nairobi, 2013)
Terminalia brownii is an African medicinal plant used to treat parasitic and microbial infections. A new oleanane-type triterenoid was isolated from its stem bark extract by bioassay-guided fractionation using the method ...
Phytochemical Evaluation of So me Kenyan Medicinal Plants
(2010)
11
th
NAPRECA Symposium Book of Proceedings, Antananarivo, Madagascar Pages 9-19
Midiwo et al.
9
Phytochemical Evaluation of So
me Kenyan Medicinal Plants
J. Ogweno Midiwo, A. Yenesew, B.F. Juma
Kerubo L Omosa, ...
Antimicrobial Abietane Diterpenoids from Clerodendrum eriophyllum
(2010)
Clerodendrum eriophyllum Gürke (Verbenaceae) is a shrub or small tree distributed in the dry bushlands of Eastern Kenya. The plant has no record of previous phytochemical analysis. A bioassay guided isolation of the methanol ...
Phytochemical, Antiparasitic and Antimicrobial Investigations of Terminalia brownii
(2013)
Terminalia brownii is an African medicinal plant used to treat parasitic and microbial infections [1]. Chromatographic separations on the stem bark extract aimed at identifying the active components led to isolation of a ...
Insect antifeedant, growth-inhibiting and larvicidal compounds from Rapanea melanphloes (Myrsinaceae)
(2011)
The already known benzoquinone, embelin (mixed with rapanone), and two new benzoquinones, myrsinone and myrsinaquinone, were isolated from the Myrsinaceae plant, Rapanea melanphloes (L), Mez. All the three compounds showed ...
Synthesis, structural assignments and antiinfective activities of 3-O-benzyl-carvotacetone and 3-hydroxy-2-isopropyl-5-methyl-p-benzoquinone.
(University of Nairobi, 2020)
In an attempt to synthesize carvotacetone analogues, new 3-O-benzyl-carvotacetone (10) and previously reported 3-hydroxy-2-isopropyl-5-methyl-p-benzoquinone (11) were synthesized from piperitone (7). In this work, we ...
The Chemistry of African Croton species
(University of Nairobi, 2016)
The genus Croton is one of the largest of Euphorbiaceae sensu stricto, and consists of over 1300 species of trees, shrubs and herbs that are distributed worldwide in the warm tropics and subtropics. It is reported that 124 ...