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Now showing items 21-30 of 31
Synthesis, structural assignments and antiinfective activities of 3-O-benzyl-carvotacetone and 3-hydroxy-2-isopropyl-5-methyl-p-benzoquinone.
(University of Nairobi, 2020)
In an attempt to synthesize carvotacetone analogues, new 3-O-benzyl-carvotacetone (10) and previously reported 3-hydroxy-2-isopropyl-5-methyl-p-benzoquinone (11) were synthesized from piperitone (7). In this work, we ...
The Chemistry of African Croton species
(University of Nairobi, 2016)
The genus Croton is one of the largest of Euphorbiaceae sensu stricto, and consists of over 1300 species of trees, shrubs and herbs that are distributed worldwide in the warm tropics and subtropics. It is reported that 124 ...
Diterpenoids from the roots of Croton dichogamus Pax.
(University of Nairobi, 2017-12)
Four previously undescribed diterpenoids including two crotofolanes, crotodichogamoin A and B, and two halimanes, crothalimene A and B, a new sesquiterpenoid, and fifteen previously reported compounds, including the ...
Study of anti-tuberculosis activity behaviour of natural Kaurane and trachylobane diterpenes compared with structural properties obtained by theoretical calculations
(University of Nairobi, 2017)
A set of seven diterpenes, three kauranes and four trachylobanes, isolated from the African plant Psiadia punctulata were assayed against Mycobacterium tuberculosis and reached activity comparable with cycloserine, a second ...
Cytotoxicity of Plumbagin, Rapanone and 12 other naturally occurring Quinones from Kenyan Flora towards human carcinoma cells.
(University of Nairobi, 2016)
BACKGROUND:
Cancer is a major public health concern globally and chemotherapy remains the principal mode of the treatment of various malignant diseases.
METHODS:
This study was designed to investigate the cytotoxicity ...
Isolation of a new β-carboline alkaloid from aerial parts of Triclisia sacleuxii and its antibacterial and cytotoxicity effects.
(University of Nairobi, 2017)
A new β-carboline alkaloid named sacleuximine A (1) together with known compounds palmatine (2), isotetrandrine (3), trans-N-feruloyltyramine (4), trans-N-caffeoyltyramine (5), yangambin (6), syringaresinol (7), sesamin ...
Toxicity and growth-inhibitory activity of Polygonum senegalense (Meissn.) surface exudate against Aedes aegypti larvae
(1998)
Laboratory studies were conducted to assess the toxicity and growth-inhibitory activity against Aedes aegypti larvae, of the crude acetone extracts of Polygonum senegalense (Meissn.) leaves, its flavonoid component ...