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Diterpenoids from the roots of Croton dichogamus Pax.
(University of Nairobi, 2017-12)
Four previously undescribed diterpenoids including two crotofolanes, crotodichogamoin A and B, and two halimanes, crothalimene A and B, a new sesquiterpenoid, and fifteen previously reported compounds, including the ...
Target-similarity search using Plasmodium falciparum proteome identifies approved drugs with anti-malarial activity and their possible targets.
(University of Nairobi, 2017)
Malaria causes about half a million deaths annually, with Plasmodium falciparum being responsible for 90% of all the cases. Recent reports on artemisinin resistance in Southeast Asia warrant urgent discovery of novel drugs ...
Dominant Allele Phylogeny and Constitutive Subgenome Haplotype Inference in Bananas Using Mitochondrial and Nuclear Markers.
(University of Nairobi, 2017)
Cultivated bananas (Musa spp.) have undergone domestication patterns involving crosses of wild progenitors followed by long periods of clonal propagation. Majority of cultivated bananas are polyploids with different ...
2-Butanone as a carbon dioxide mimic in attractant blends for the Afrotropical malaria mosquitoes Anopheles gambiae and Anopheles funestus.
(University of Nairobi, 2017)
BACKGROUND:
Most odour baits designed to attract host-seeking mosquitoes contain carbon dioxide (CO2), which enhances trap catches, given its role as a mosquito flight activator. However, the use of CO2 is expensive and ...
First comprehensive study on total contents and hot water extractable fraction of selected elements in 19 medicinal plants from various locations in Nyamira County, Kenya.
(University of Nairobi, 2017)
A large number of medicinal plants is traditionally known in Kenya and used for treatment of various diseases, for example diabetes, where metals are supposed to be involved in pathogenesis and therapy. Therefore, detailed ...
Antiplasmodial prenylated flavanonols from tephrosia subtriflora
(2017)
The CH2Cl2/MeOH (1:1) extract of the aerial parts of Tephrosia subtriflora afforded a new flavanonol, named subtriflavanonol (1), along with the known flavanone spinoflavanone B, and the known flavanonols MS-II (2) and ...
An assessment of e-extension platforms in Kenya
(University of Nairobi, 2017-07)
The use of ICT in agriculture within
developing countrie
s has quickly gained popularity
among development agencies, the private sector and
even the government. ICT for ...
Study of anti-tuberculosis activity behaviour of natural Kaurane and trachylobane diterpenes compared with structural properties obtained by theoretical calculations
(University of Nairobi, 2017)
A set of seven diterpenes, three kauranes and four trachylobanes, isolated from the African plant Psiadia punctulata were assayed against Mycobacterium tuberculosis and reached activity comparable with cycloserine, a second ...
Novel Rickettsia and emergent tick-borne pathogens: A molecular survey of ticks and tick-borne pathogens in Shimba Hills National Reserve, Kenya
(University of Nairobi, 2017-02)
Ticks are important vectors of emerging and re-emerging zoonoses, the majority of which originate from wildlife. In recent times, this has become a global public health concern that necessitates surveillance of both known ...
The global ethics corner: foundations, beliefs, and the teaching of biomedical and scientific ethics around the world.
(University of Nairobi, 2017)
The profound advances in the biomolecular sciences over the last decades have enabled similar advances in biomedicine. These advances have increasingly challenged our abilities to deploy them in an equitable and ethically ...