Faculty of Science & Technology (FST): Recent submissions
Now showing items 81-100 of 4283
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Comparative in silico study of congocidine congeners as potential inhibitors of African swine fever virus
(University of Nairobi, 2019)African swine fever virus (ASFV) infection is fatal in domesticated pigs, with a mortality rate approaching 100%. This may result in economic losses and threats to food security. Currently, there are no approved vaccines ... -
Risk factors for the incursion, spread and persistence of the foot and mouth disease virus in Eastern Rwanda
(University of Nairobi, 2020)Background: Identification of risk factors is crucial in Foot-and-mouth disease (FMD) control especially in endemic countries. In Rwanda, almost all outbreaks of Foot-and-Mouth Disease Virus (FMDV) have started in Eastern ... -
Two novel lignans derivatives and two fusicoccane diterpenoids from whole plant of Hypoestes verticillaris (L.f.) Sol. ex Roem. & Schult
(University of Nairobi, 2019)Bioassay-guided screening of Hypoestes verticillaris whole plant CH2Cl2:MeOH (1:1) extract for anti-plasmodial activity yielded four new compounds: two lignans 2, 6-dimethoxysavinin (1), 2,6-dimethoxy-(7E)-7,8-dehydrohel ... -
Rapid Screening using GIBEX Screens-to-nature System of Ethnomedicinal Plants from Ngong Forest, Kenya for Potency against Infectious Diseases and Antioxidant Activities: A Qualitative Study
(University of Nairobi, 2019)Introduction: Plants from Kenyan flora are traditionally used to manage a number of ailments including; chronic and infectious disease, to bolster the body immunity and for general health protections. The current investigation ... -
Oleanolic Acid and other Compounds Isolated from Cordia africana Lam which Inhibit Vancomycin Resistant Enterococcus
(University of Nairobi, 2019)ABSTRACT Introduction: Treatment of microbial infections has become complicated due to increased resistance of microbes to the current drugs. The current study investigates crude extracts and seven compounds from root ... -
Antiplasmodial Biflavanones from the Stem Bark of Garcinia buchananii Engl.
(University of Nairobi, 2019)Introduction: Plants of the genus Garcinia are traditionally used treat a range of infectious and non-infectious diseases. Garcinia species are reported to have been shown to have a range of biological activities including ... -
Antiproliferative Properties of Labdane Diterpenoids from Croton sylvaticus Hochst against Drug Sensitive and Resistant Leukemia cell lines
(University of Nairobi, 2019)Background: Cancer treatment failure is majorly attributed to the emergency of multi-drug resistance of cancer cells towards most conventional drugs used in chemotherapy hence the need for more active principles with less ... -
Anti-leishmanial activity of some surface compounds of Tarchonanthus camphoratus
(University of Nairobi, 2019)Background: The World Health Organization recognizes leishmaniasis as a major tropical disease with no effective vaccine against it. Chemotherapy, the only effective way to treat all forms of the disease, is toxic and ... -
In vitro Antiplasmodial and Cytotoxic activity of Three Medicinal Plants used Traditionally for Treatment of Malaria
(University of Nairobi, 2020)Introduction: Reports of emergence of Artemisinin Combination Therapies (ACTs) resistant malaria parasites in Greater Mekong region and Equatorial Guinea, is a strong reason necessitating increased efforts to discover new ... -
Two new flavonoids from Dracaena usambarensis Engl.
(University of Nairobi, 2020)Investigations of the root extract of Dracaena usambarensis Engl. for anticancer principles led to the characterization of one new homoisoflavonoid, (3S)-3,4ʹ,5,6-tetrahydroxy-7-methoxyhomoisoflavanone (1) and a new ... -
Adaptation to Climate Change - Induced Malaria and Cholera in the Lake Victoria Region
(University of Nairobi, 2018)AIACC Working Papers, published on-line by Assessments of Impacts and Adaptations to Climate Change (AIACC), is a series of papers and paper abstracts written by researchers participating in the AIACC project. Papers published ... -
Determinants of Household Food Security Status and Challenges of Building Resilience to Climate Variability and Change Posed by Drought in Tharaka Nithi, Kenya
(University of Nairobi, 2018)Climate change and variability pose momentous severe threats to agricultural development and consequently to economic growth and increased poverty levels. In reference, this paper examines the determinants of household ... -
Analysis of Total Petroleum Hydrocarbons in Water from Ngong and Mathare Rivers, Nairobi County, Kenya
(University of Nairobi, 2018)Unsustainable industrial development has created negative impacts to global ecosystem quality and biodiversity due to increased load of chemical and biological contaminants released into environment. Ecological ... -
Smallholder Farmers Vulnerability Level to Climate Change Impacts and Implications to Agricultural Production in Tigray Regional State, Northern Ethiopia
(University of Nairobi, 2019)Vulnerability to climate change impact is the most pressing issues for less developed countries whose economy mainly depends on the agricultural sector. The demand for food is growing swiftly whereas impacts of climate change ... -
Impact of Renewable Technology on Lignocellulosic Material of Palm Fruit Fibre: Strategy for Climate Change and Adaptation
(University of Nairobi, 2019)Harmful gases are released into the atmosphere through burning of residues which is commonly practiced in Nigeria and can be attributed to climate change issues. Agricultural residues have the potentials to be used as ... -
Analysis of Average Annual Rainfall and Average Maximum Annual Temperature for a Period of 30 years to Establish Trends in Kieni, Central
(University of Nairobi, 2019)The aim of the study was to analyze average annual rainfall and average maximum annual temperature records for 30 years in the study area to establish trends hence confirm the presence or absence of climate change. The ... -
New Palladium II and Platinum II Complexes Based on Pyrrole Schiff Bases- Synthesis, Characterization, X‑ray Structure, and Anticancer Activity
(University of Nairobi, 2020)New palladium (Pd)II and platinum (Pt)II complexes (C1−C5) from the Schiff base ligands, R-(phenyl)methanamine (L1), R-(pyridin-2-yl)methanamine (L2), and R-(furan- 2-yl)methanamine (L3) (R-(E)-N-((1H-pyrrol-2-yl) ... -
Occurrence, abundance and distribution of benthic macroinvertebrates in the Nyando River catchment, Kenya
(University of Nairobi, 2015)A baseline study was conducted of the occurrence of macroinvertebrates at 26 sites in the Nyando River catchment in 2005–2006. A total of 13 orders and 16 families of Arthropoda, Mollusca, Platyhelminthes and Annelida ... -
Comparison of the Effectiveness of Various Designs of Ceramic Filter Membranes in Domestic Water Purification
(University of Nairobi, 2019)This research aimed to compare the effectiveness of three different types of ceramic water filters (Disk, Candle and Frustum shaped) in treating drinking water. The ceramic water filters were made from red clay and sawdust ... -
Compositional Analysis and Optical Properties of Co Doped Tio2 Thin Films Fabricated by Spray Pyrolysis Method for Dielectric and P Hotocatalytic Applications
(University of Nairobi, 2017)Abstract Cobalt doped TiO2 thin films (CTF) deposited by spray pyrolysis has been studied. The compositional analysis has been done using RBS method, while optical spectroscopy has been done by measuring the transmittance ...