dc.contributor.author | JF, Weis | |
dc.contributor.author | McClelland, RS | |
dc.contributor.author | Jaoko, W | |
dc.contributor.author | Mandaliya, KN | |
dc.contributor.author | Overbaugh, J | |
dc.date.accessioned | 2015-02-11T09:04:49Z | |
dc.date.available | 2015-02-11T09:04:49Z | |
dc.date.issued | 2014 | |
dc.identifier.citation | Weis JF, McClelland RS JMKNOGSMWJ &. "Fc Gamma Receptors IIa and IIIa Genetic polymorphisms do not predict HIV-1 disease progression in Kenyan women. ." AIDS Res Hum Retroviruses (in print). 2014. | en_US |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pubmed/25312792 | |
dc.identifier.uri | http://hdl.handle.net/11295/80211 | |
dc.description.abstract | Abstract Genetic polymorphisms of the Fc gamma receptors (FcγR) IIa and IIIa have been implicated in the rate of HIV-1 disease progression, but results are inconsistent. We aimed to determine the association between these polymorphisms and disease progression in a cohort of HIV-1 seroconverters from Mombasa, Kenya. Neither FcγRIIa nor FcγRIIIa genotypes were predictive of set point viral load, viral load increase, CD4 decline, or HIV-1 disease progression (time to CD4 count <200 cells/mm3, death, or treatment initiation). Our results suggest that FcγR polymorphisms might not be an important indicator of viral control and disease progression in this population. | en_US |
dc.language.iso | en | en_US |
dc.title | Fc Gamma Receptors IIa and IIIa Genetic Polymorphisms Do Not Predict HIV-1 Disease Progression in Kenyan Women. | en_US |
dc.type | Article | en_US |
dc.type.material | en | en_US |