Browsing Faculty of Health Sciences (FHS) by Title
Now showing items 5367-5386 of 10378
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Khat (Catha edulis)-induced apoptosis is inhibited by antagonists of caspase-1 and -8 in human leukaemia cells.
(University of Nairobi,Department of Oral and Maxillofacial Radiology, 2004-11)Khat chewing is a widespread habit that has a deep-rooted sociocultural tradition in Africa and the Middle East. The biological effects of khat are inadequately investigated and controversial. For the first time, we show ... -
Khat (Catha edulis)-induced apoptosis is inhibited by antagonists of caspase-1 and-8 in human leukaemia cells
(2004)Khat chewing is a widespread habit that has a deep-rooted sociocultural tradition in Africa and the Middle East. The biological effects of khat are inadequately investigated and controversial. For the first time, we show ... -
Khat and Oral Cancer.
(University of NairobiSchool of Dental Sciences, 2002) -
khat induced apoptosis is inhibited by antagonists of caspase - 1 and 8 in human leukaemia cells
(School of Dental Sciences, University of Nairobi, 2004) -
Khat induces G1‐phase arrest and increased expression of stress‐sensitive p53 and p16 proteins in normal human oral keratinocytes and fibroblasts
(Department of Oral/Maxillofacial Surgery, Oral Medicine/Pathology, Oral/Maxillofacial Radiology, 2008)Khat is a psychostimulant plant used by over 10 million people daily, mainly in eastern Africa and the Middle East. Previous studies have suggested an association between khat use and oral lesions such as hyperkeratosis ... -
Khat use and khat induced oral white lesions among khat and tobacco users at two sites in Kenya
(2015)Abstract Background: Long term chewing of khat is associated with white lesions on the oral mucosa some of which depict histopathological changes. However, due to the limited number of studies in this area, the clinical ... -
Khat Use, PTSD and Psychotic Symptoms among Somali Refugees in Nairobi - A Pilot Study.
(University of Nairobi, 2014-06)In East-African and Arab countries, khat leaves are traditionally chewed in social settings. They contain the amphetamine-like alkaloid cathinone. Especially among Somali refugees, khat use has been associated with psychiatric ... -
Khat-induced paranoid psychosis
(Department of Pharmacy, University of Nairobi, 1988) -
Ki-67 antigen in ameloblastomas: correlation with clinical and histological parameters in 54 cases from Kenya
(College of Health Sciences, University of Nairobi, 1997)The aim of this study was to assess the cell proliferation in ameloblastomas and to correlate this with clinical features and histology. Immunohistochemistry with Ki-67 monoclonal antibody was performed on fresh tissue ... -
Kidney transplantation: recent medical experiences from the Kenyatta National Hospital, Nairobi.
(Department of Medicine, University of Nairobi, 1996)Renal transplantation is not readily available in the majority of countries in Africa. It is expensive and difficult to sustain on the meagre funds allocated to health. We report our short experience with fifteen living ... -
The kinase inhibitory region of SOCS-1 is sufficient to inhibit T-helper 17 and other immune functions in experimental allergic encephalomyelitis.
(2011-03)Suppressors of cytokine signaling (SOCS) negatively regulate the immune response, primarily by interfering with the JAK/STAT pathway. We have developed a small peptide corresponding to the kinase inhibitory region (KIR) ... -
Kinetics and mechanisms of glutamate transport across the mitochondrial membrane
(Department of Biochemistry, University of Nairobi, 1980)The kinetics of glutamate influx and efflux on the glutamate-hydroxyl carrier have been measured and compared in rat liver mitochondria. At pH 7.4 and 25 degrees C, the Michaelis constants and V'max values were in agreement ... -
Kinetics of hydrolysis of monoamino analogues of 2'- or 3'-deoxyadenosine and 2'- or 3'-deoxy- 9-(ß-D-lyxo-pentofuranosyl)adenine
(University of Nairobi, 1995)No abstract available -
The kinetics of salivary elimination of cyclophosphamide in man.
(1979)The concentrations of cyclophosphamide in plasma and saliva were determined in seven patients following administration of single doses of cyclophosphamide during chemotherapy for lymphoma. 2 The saliva/plasma ratio was ... -
Kinetics, distribution, and efficacy of ceftriaxone versus cefazolin in open heart surgery.
(1984)The effects of cardiopulmonary bypass (CPB) with hypothermia and systemic heparinization on ceftriaxone disposition were evaluated in seven male patients. A bolus dose of drug (14 mg/kg of body weight) was given, and blood ... -
Kirin Information on Drugs and Science Journal
(University of NairobiDepartment of Dental Science, 2001) -
Klinefelter's syndrome in Kenyan patients
(Department of Psychiatry, University of Nairobi, Nairobi, Kenya;, 1984-02) -
Knowledge and adherence to the national guidelines for malaria case management in pregnancy among healthcare providers and drug outlet dispensers in rural, western Kenya
(University of Nairobi, 2016)Background Although prompt, effective treatment is a cornerstone of malaria control, information on provider adherence to malaria in pregnancy (MIP) treatment guidelines is limited. Incorrect or sub-optimal treatment ... -
Knowledge and attitude of MTCT of HIV among women in Karatina and Homabay Hospitals before and after counseling
(Department of Nursing Sciences, University of Nairobi., 2005)This project is part of the 11 country PMTC project of UNICEF, UNAIDS and WHO. The Three Kenyan sites supported by NARESA and MOH are KNH, Karatina and Homabay. Operations research is supported by Horizons and USAID. The ... -
Knowledge and attitudinal study of Kenyan women in relation to cervical carcinoma
(Department of Obstetrics and Gynaecology, College of Health Sciences, University of Nairobi, Kenya, 1991)Knowledge and attitude in relation to cervical carcinoma was studied in 85 cervical cancer patients and 177 matched controls. The mean age of the cases was 44.2 years and mean parity 6.5. The majority were illiterate. ...