Browsing Faculty of Health Sciences (FHS) by Title
Now showing items 6052-6071 of 10378
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Modified vaccinia Ankara expressing HIVA antigen stimulates HIV-1-specific CD8 T cells in ELISpot assays of HIV-1 exposed infants[star]
(Department of Medical MicrobiologyDepartment of Paediatrics, 2005)Recombinant modified vaccinia virus Ankara expressing HIV-1 antigens (MVA.HIVA) was used in ELISpot assays to monitor HIV-1-specific T cell responses in infants. Responses to MVA.HIVA and HIV-1 peptides were examined in ... -
Modulation and evaluation of the degree of crosslinking in gelatin hydrogel matrices using a water soluble carbodiimide
(University of NairobiCollege of Health Sciences,University of Nairobi, 1995) -
Modulators of the efficacy and toxicity of drugs in malaria treatment.
(University of Nairobi,College of Health Sciences,, 2010-06)The burgeoning problem of drug resistance in malaria requires the urgent discovery of new drugs. Discovery of an antimalarial agent that fulfills the requirements of a mass-treatment drug is challenging. Such an antimalarial ... -
Molecular adsorbent and re-circulating system
(Department of Medicine, College of Health Sciences, University of Nairobi, 2004)The molecular adsorbent recirculating system (MARS) is a non-biological artificial liver support system. Used for almost a decade, there are only two randomized controlled trials on the efficacy of MARS till date. A number ... -
Molecular Characterization and Phylogenetic Analysis of the Hemagglutinin 1 Protein of Human Influenza A Virus Subtype H1N1 Circulating in Kenya During 2007–2008
(University of Nairobi.College of Health Sciences, University of Nairobi, Kenya, 2012)Background.Among influenza viruses, type A viruses exhibit the greatest genetic diversity, infect the widest range of host species, and cause the vast majority of cases of severe disease in humans, including cases during ... -
Molecular Characterization of a Novel Plasmid-Encoded Cefotaximase (CTX-M-12) Found in Clinical Klebsiella pneumoniae Isolates from Kenya
(University of Nairobi,Department of Paediatric & Microbiology, 2001)Nine Klebsiella pneumoniae isolates, six from blood and three from cerebrospinal fluid of newborn babies at Kenyatta National Hospital, Nairobi, Kenya, were analyzed for the mechanism of cephalosporin resistance. By using ... -
Molecular characterization of a tsetse fly midgut proteolytic lectin that mediates differentiation of African trypanosomes.
(2006)Differentiation of bloodstream-form trypanosomes into procyclic (midgut) forms is an important first step in the establishment of an infection within the tsetse fly. This complex process is mediated by a wide variety of ... -
Molecular characterization of fluoroquinolone resistance genes in isolates obtained from patients with diarrhea in Machakos district hospital, Kenya
(University of Nairobi, 2016)Background: Diarrhea caused by Enterobacteriaceae such as Shigella species and Escherichia coli (E. coli) is endemic throughout the world, and is one of the most important causes of global childhood mortality and morbidity. ... -
Molecular Characterization of HIV Type 1 Among HIV-Infected Respondents in a Cohort Being Prepared for HIV Phase III Vaccine Clinical Trials, Western Kenya
(Kenyatta University, Department of Biological Sciences, Nairobi, KenyaKenya Aids Vaccine Initiative (KAVI), Department of Medical Microbiology, University of NairobiDivision of Medical Virology, National Health Laboratory Services (NHLS) and University of Stellenbosch, Tygerberg, South Africa, 2011)Kenya is one of the sub-Saharan African countries affected by HIV-1 infection and AIDS. We investigated HIV-1 genetic diversity in 130 individuals from Busia, Bungoma, and Kakamega in western Kenya as part of an HIV-1 ... -
Molecular characterization of human coronavirus circulating in Kenya, 2009-2012
(University of Nairobi, 2014)Background: The genome of a human coronavirus (HCoV) is composed of a linear, single-stranded, non-segmented, positive-sense RNA of 27-32 kb. The pol gene of HCoV found in ORF1ab, is a good molecular chronometer for molecular ... -
Molecular characterization of human coronaviruses and their circulation dynamics in Kenya, 2009-2012.
(University of Nairobi, 2016)Background Human Coronaviruses (HCoV) are a common cause of respiratory illnesses and are responsible for considerable morbidity and hospitalization across all age groups especially in individuals with compromised ... -
Molecular characterization of human parainfluenza virus type 1 in infants attending Mbagathi district hospital, Nairobi, Kenya: a retrospective study
(University of Nairobi, 2013-12)Human parainfluenza virus type 1 (HPIV-1), a paramyxovirus, is a leading cause of pediatric respiratory hospitalizations globally. Currently, there is no clinically successful vaccine against HPIV-1. Hence, there is a need ... -
Molecular characterization of Theileria parasites: application to the epidemiology of theileriosis in Zimbabwe.
(Univesity of NairobiDepartment of Medicine, 1994-12)Forty Theileria schizont-infected lymphocyte culture isolates from Zimbabwe were characterized using a panel of antischizont monoclonal antibodies (MAbs) and 4 Theileria parva DNA probes containing cloned extrachromosomal ... -
Molecular cloning and characterization of viruses isolated from chimpanzees with pathogenic human immunodeficiency virus type 1 infections.
(1998)We have previously described the development of AIDS in a chimpanzee (C499) infected with human immunodeficiency virus type 1 (HIV-1) and the subsequent pathogenic HIV-1 infection in another chimpanzee (C455) transfused ... -
Molecular Definition Of Vaginal Microbiota In East African Commercial Sex Workers
(University of NairobiDepartment of Infectious Diseases, 2011-06)Resistance to HIV infection in a cohort of commercial sex workers living in Nairobi, Kenya, is linked to mucosal and antiinflammatory factors that may be influenced by the vaginal microbiota. Since bacterial vaginosis (BV), ... -
Molecular detection and genetic characterization of kobuviruses and astroviruses in asymptomatic local pigs in East Africa
(University of Nairobi., 2013-12)In this study, swine fecal specimens (n = 251) collected from nursing and weaned piglets raised under smallholder production systems were screened for the presence of kobuviruses by RT-PCR. Porcine kobuviruses were detected ... -
Molecular detection of enterotoxigenic escherichia coli surface antigens from patients in Machakos district hospital, Kenya
(University of Nairobi, 2014)Introduction: Enterotoxigenic Escherichia coli (ETEC) is known for its public health importance globally, however, a protective vaccine is yet to be developed. Information regarding the immunology of ETEC’s ... -
Molecular diversity of HIV-1 and prevalence of hepatitis B and C viruses among HIV-infected patients from selected districts in western Kenya
(University of NairobiCollege of Health Sciences,University of Nairobi, 2010-10) -
Molecular epidemiology of measles virus in Kenya.
(University of Nairobi.Department of Paediatrics, 2003-12)Measles causes significant morbidity and mortality globally. Many countries have embarked on immunization programs to control and prevent measles outbreaks and eventually to eliminate endemic measles. Kenya is currently ... -
Molecular epidemiology of Theileria orientalis in Australia and development of a molecular method for differentiation of T. orientalis genotypes
(Department of Biochemistry, 2011)