Browsing Faculty of Health Sciences (FHS) by Title
Now showing items 6072-6091 of 10378
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Molecular evidence confirms occurrence of Rhipicephalus microplus Clade A in Kenya and sub-Saharan Africa.
(University of Nairobi, 2020)Background The tick vector Rhipicephalus microplus which transmits Babesia spp. and rickettsial pathogens has not been reported in Kenya since 1998. More recently, the pathogenic Babesia bovis has been detected in cattle ... -
Molecular Genetic Analysis Of FIH-1, FH, And SDHB Candidate Tumour Suppressor Genes In Renal Cell Carcinoma.
(Department of Biochemistry, 2004-07)Overexpression of the hypoxia inducible factor 1 (HIF-1) and HIF-2 transcription factors and the consequent upregulation of hypoxia inducible mRNAs is a feature of many human cancers and may be unrelated to tissue hypoxia. ... -
Molecular interactions in the phenomenology of the onset of mental illness
(University of Nairobi, 1973-07)The requirements for a normal functioning of the central nervous system (CNS) are discussed with particular reference to the rigorous separation among central neurotransmitters. Any leak of a transmitter into synapses of ... -
Molecular Methods for Mycobacterium tuberculosis strain typing-Users guide. J Appl Microbio 94:781-791
(University of NairobiSchool of medicine, 2003)No abstract available -
Molecular monitoring of the Leu-164 mutation of dihydrofolate reductase in a highly sulfadoxine/pyrimethamine-resistant area in Africa
(University of NairobiCollege of Health Sciences, 2003-12)The selection of point mutation at codon 164 (from isoleucine to leucine) of the dihydrofolate reductase (DHFR) enzyme in Plasmodium falciparum is associated with high sulfadoxine /pyrimethamine (SP) resistance. Using the ... -
Molecular Profiling of Kenyan Acute Myeloid Leukemia Patients
(University of Nairobi, 2022)Acute myeloid leukemia (AML) is an infrequent disease, and it is associated with high morbidity and mortality. It harbors a unique configuration of cytogenetic abnormalities and molecular mutations that can be detected ... -
Molecular profiling of LGL leukemia reveals role of sphingolipid signaling in survival of cytotoxic lymphocytes.
(Penn State Hershey Cancer Institute, Milton S. Hershey Medical College, Hershey, PA, USA., 2008)T-cell large granular lymphocyte (LGL) leukemia is characterized by clonal expansion of CD3(+)CD8(+) cells. Leukemic LGLs correspond to terminally differentiated effector-memory cytotoxic T lymphocytes (CTLs) that escape ... -
The molecular relationship between HBV infection and hepatoma in Kenya.
(University of NairobiSchool of medicine, 1985) -
Molecular signatures of immune activation and epithelial barrier remodeling are enhanced during the luteal phase of the menstrual cycle: implications for HIV susceptibility
(University of Nairobi, 2015)Variable infectivity and transmissibility of HIV/SHIV has been recently associated with the menstrual cycle, with particular susceptibility observed during the luteal phase in non-human primate models and ex vivo human ... -
Molecular surveillance of adamantane resistance among human influenza a viruses isolated in four epidemic seasons in Kenya
(University of Nairobi, 2016)Background: Adamantanes impede influenza A virus replication and are important in the treatment and prophylaxis of disease caused by these viruses. Genotypic characterization of influenza A viruses for mutations associated ... -
Molecular typing of respiratory human enteroviruses isolated in Kenya between 2008 -2011 using the VP1 gene
(University of Nairobi, 2014)Background: Human enteroviruses (genus Enterovirus, family Picornaviridae) are common infectious agents grouped into HEV-A, HEV-B, HEV-C and HEV-D species. They comprise >100 serotypes and are responsible for a wide range ... -
Mondia whitei, a medicinal plant from Africa with aphrodisiac and antidepressant properties: a review
(2012)This paper reviews the literature concerning the ethnobotany, phytochemistry, and pharmacology of Mondia whitei, which is also known as Mondia whytei, African ginger or simply as mondia. Mondia is used in many parts of ... -
Monitoring technologist reading skills in a sperm morphology quality control program
(Department of Human Pathology, 2003-06)The value of sperm morphology as a predictor of a man’s fertilizing potential has often been challenged because of different classification systems used to distinguish between normal and abnormal spermatozoa. The study ... -
Monoclonal antibodies against boar sperm zona pellucida-binding protein AWN-1. Characterization of a continuous antigenic determinant and immunolocalization of AWN epitopes in inseminated sows
(Institut für Reproduktionsmedizin, Tierärztliche Hochschule, Hannover, Germany. jcalvete@repro.tiho-hannover.de, 1997)Boar spermadhesin AWN-1 is a sperm surface-associated 14.7-kDa lectin and a major protein of porcine seminal plasma. AWN-1 binds to beta-galactosides and to porcine zona pellucida glycoproteins, suggesting that this protein ... -
Monthly antibiotic chemoprophylaxis and incidence of sexually transmitted infections and HIV-1 infection in Kenyan sex workers: a randomized controlled trial.
(Department of MedicaL MicrobioLogy, College of HeaLth Sciences, University of Nairobi, Nairobi, Kenya, 2004-06)CONTEXT: Sexually transmitted infections (STIs) are common in female sex workers (FSWs) and may enhance susceptibility to infection with human immunodeficiency virus type 1 (HIV-1). OBJECTIVE: To examine regular ... -
Morbidity among HIV-1-infected mothers in Kenya: prevalence and correlates of illness during 2-year postpartum follow-up.
(University of Nairobi, 2007)Background: Much of the burden of morbidity affecting women of childbearing age in sub-Saharan Africa occurs in the context of HIV-1 infection. Understanding patterns of illness and determinants of disease in HIV-1–infected ... -
Morbidity among HIV-1–infected mothers in Kenya prevalence and correlates of illness during 2-year postpartum follow-up
(Department of Pediatrics, University of Nairobi, Nairobi,, 2007)Background: Much of the burden of morbidity affecting women of childbearing age in sub-Saharan Africa occurs in the context of HIV-1 infection. Understanding patterns of illness and determinants of disease in HIV-1–infected ... -
Morbidity and CD4+ Cell Counts at Initial Presentation of a Cohort of HAART-Naive, HIV Positive Kenyan Patients: Implications to Initiating HAART
(University of Nairobi, 2014)Background: Sub-Saharan Africa with under 10% of the worldfs total population accounts for 60-70% of all HIV/AIDS cases. While these patients require HAART to manage the disease, HAART is not universally available. Majority ... -
Morbidity And Mortality In Breastfed And Formula-fed Infants Of Hiv-1-infected Women: A Randomized Clinical Trial
(University of NairobiSchool of medicine (Paediatrics), 2002-11-21)CONTEXT: Breastfeeding among women infected with human immunodeficiency virus type 1 (HIV-1) is associated with substantial risk of HIV-1 transmission, but little is known about the morbidity risks associated with formula ...