Browsing Faculty of Health Sciences (FHS) by Title
Now showing items 9075-9094 of 10378
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Single-agent tenofovir versus combination emtricitabine plus tenofovir for pre-exposure prophylaxis for HIV-1 acquisition: an update of data from a randomised, double-blind, phase 3 trial.
(2014)Abstract BACKGROUND: Antiretroviral pre-exposure prophylaxis (PrEP), with daily oral tenofovir disoproxil fumarate or tenofovir disoproxil fumarate in combination with emtricitabine, has been shown to be efficacious ... -
A Single-Arm, Proof-Of-Concept Trial of Lopimune (Lopinavir/Ritonavir) as a Treatment for HPV-Related Pre-Invasive Cervical Disease
(University of Nairobi, 2016)Background Cervical cancer is the most common female malignancy in the developing nations and the third most common cancer in women globally. An effective, inexpensive and self-applied topical treatment would be an ideal ... -
Single-center randomized trial comparing tacrolimus (FK506) and cyclosporine in the prevention of acute myocardial rejection
(Department of Cardiac Surgery, University of Munich, Grosshadern Medical Center, Germany, 1998)To compare the efficacy and safety of tacrolimus and cyclosporine in heart transplantation, this single-center, prospective, randomized, open-label clinical trial was undertaken. METHODS: Seventy-three adult patients ... -
Single-dose cefixime versus single-dose ceftriaxone in the treatment of antimicrobial-resistant Neisseria gonorrhoeae infection.
(Department of Medical Microbiology, University of Nairobi, Kenya., 1992)Sexually transmitted diseases (STDs) have a significant adverse effect on reproductive and child health worldwide. The control of STDs such as gonorrhea is therefore an absolute priority. Cefixime, an oral third-generation ... -
Single-dose ceftriaxone for chancroid
(University of NairobiDepartment of Medicine, 1987-01)Men with genital ulcers that were culture positive for Haemophilus ducreyi were treated with intramuscular ceftriaxone and randomized to three different dose regimens. All but 1 of 50 men treated with 1 g of intramuscular ... -
Single-dose ceftriaxone therapy of gonococcal ophthalmia neonatorum
(University of Nairobi, 1986-01)Ceftriaxone (125 mg) given as a single intramuscular dose without topical therapy was evaluated in seven infants with smear-positive gonococcal ophthalmia neonatorum. Neisseria gonorrhoeae was isolated from the eyes of six ... -
Single-dose kanamycin therapy of gonococcal ophthalmia neonatorum
(University of Nairobi,Department of Medicine, 1984-12)117 infants with gonococcal ophthalmia neonatorum, including 27 with infections due to penicillinase-producing Neisseria gonorrhoeae, were treated as outpatients with five different regimens of single-dose intramuscular ... -
Single-dose therapy of chancroid with trimethoprim-sulfametrole
(University of Nairobi,Department of Medicine, 1983-07)We conducted a randomized double-blind trial comparing a single dose of trimethoprim-sulfametrole (640 to 3200 mg) with five-day regimens of either trimethoprim-sulfametrole (160 to 800 mg twice daily) or trimethoprim alone ... -
Single-dose therapy of gonococcal ophthalmia neonatorum with ceftriaxone
(Department of Medical Microbiology, University of Nairobi, 1986)We conducted a randomized clinical trial comparing a single intramuscular dose of 125 mg of ceftriaxone with a single intramuscular dose of 75 mg of kanamycin followed by topical gentamicin for seven days, and with a single ... -
Single-dose therapy with trimethoprim-sulfametrole for chancroid in females
(University of Nairobi,Department of Medicine, 1986-09)Women with genital ulcer disease who were culture-positive for Haemophilus ducreyi were treated with a single dose of the drug combination trimethoprim-sulfametrole; the dosage was 640 mg of trimethoprim and 3,200 mg of ... -
Single-stranded DNA oligonucleotides inhibit TLR3-mediated responses in human monocyte-derived dendritic cells and in vivo in cynomolgus macaques.
(University of Nairobischool of public health, 2012-07)TLR3 is a key receptor for recognition of double-stranded RNA and initiation of immune responses against viral infections. However, hyperactive responses can have adverse effects, such as virus-induced asthma. Strategies ... -
Sinonasal adenocarcinoma: Immunohistochemical marking and expression of oncoproteins
(University of Nairobi,School of Medicine, 2003-09-25)Background: Relatively little is known concerning the immunohistochemical marking of sinonasal adenocarcinoma (SNA). The most clinically problematic tumors are those that seem histologically identical to colonic adenocarcinoma, ... -
Site of the abnormal stimulus of gastric secretion after small bowel exclusion.
(University of NairobiSchool of medicine, 1972-07)In dogs with either vagally innervated or denervated pouches, the acid responses to a standard meal, a meal which bypassed the greater part of the small bowel, and a meal introduced directly into the small intestine were ... -
A Situation Assessment of Community Health Workers' Preparedness in Supporting Health System Response to Covid-19 in Kenya, Senegal, and Uganda
(University of Nairobi, 2022)Background: Coronavirus disease (COVID-19) caused socio-economic disruptions across the globe. The pandemic disrupted the health system (HS) calling for reengineering in response to high infection rates, deaths, and resultant ... -
A situational analysis of the mental health system of the West Region of Cameroon using the World Health Organization's assessment instrument for mental health systems
(University of Nairobi, 2022-03)Background: The publication of the World Health Report of 2001 by the World Health Organization (WHO) raised awareness of mental health worldwide. It reported a higher burden of mental illnesses in developing countries, ... -
A situational analysis on heart disease in urban and rural Kenya
(University of NairobiDepartment Of Human Anatomy, University Of Nairobi., 2007)BACKGROUND: With the purpose of providing a new tool in the prevention of cardiovascular disease, which is fast becoming the first cause of morbidity and mortality in the World, the idea of utilizing young medicine students’ ... -
Six stormy years and the audacity to confront a challenging future: taking stock of the Kenyan Doctors' Union.
(University of Nairobi, 2018)The Kenya Medical Practitioners, Pharmacists and Dentists Union (KMPDU) was formed in August 2011. Within the last six years, this union has galvanized the Kenyan doctors together, agitated for healthcare policy reforms ...