Browsing Faculty of Health Sciences (FHS) by Author "MacDonald, Kelly S"

Now showing items 1-3 of 3

    • Late seroconversion in HIV-resistant Nairobi prostitutes despite pre-existing HIV-specific CD8+ responses 

      Rupert, Kaul; Rowland-Jones, Sarah L.; Kimani, Joshua; Dong, Tao; Hong-Bing, Yang; Kiama, Peter; Rostron, Timothy; Njagi, Ephantus; Bwayo, JJ; MacDonald, Kelly S; McMichael, Andrew J; Plummer, Francis A (University of NairobiDepartment of Medicine, 2001-02-01)
      Resistance to HIV infection in a small group of Kenyan sex workers is associated with CD8+-lymphocyte responses to HIV cytotoxic T-lymphocyte (CTL) epitopes. Eleven prostitutes meeting criteria for HIV resistance seroconverted ...

    • Persistently HIV-1 seronegative Nairobi sex workers are susceptible to in vitro infection 

      Bienzle, Dorothee; MacDonald, Kelly S; Copeland, Karen F T; Bwayo, JJ; Plummer, Francis A; Rosenthal, Kenneth L (Department of Medical Microbiology, 2000)
      OBJECTIVE: To evaluate whether resistance to HIV-1 infection in a subset of highly exposed sex workers correlates with resistance at the cellular level. DESIGN: In vitro evaluation of susceptibility to infection by ...

    • Sequence and peptide-binding motif for a variant of HLA-A*0214 (A*02142) in an HIV-1-resistant individual from the Nairobi Sex Worker cohort 

      Luscher, Mark A; MacDonald, Kelly S; Bwayo, JJ; Plummer, FA; Barber, Brian H (Springer-VerlagDepartment of Medicine, University of Toronto, Toronto, Canada,Department of Microbiology, Mount Sinai Hospital, Room 1484, 600 University Ave., Toronto, Ontario, M5G 1X5, Canada,Department of Microbiology, University of Nairobi, Nairobi, Kenya,Department of Medical Microbiology University of Manitoba, Winnipeg, CanadaDepartment of Immunology, University of Toronto, Toronto, Canada,, 2001)
      As part of the ongoing study of natural HIV-1 resistance in the women of the Nairobi Sex Workers' study, we have examined a resistance-associated HLA class I allele at the molecular level. Typing by polymerase chain reaction ...