Browsing Faculty of Health Sciences (FHS) by Author "MacDonald KS."

Now showing items 1-4 of 4

    • HIV-1-specific mucosal IgA in a cohort of HIV-1-resistant Kenyan sex workers 

      Kaul, R; Trabattoni, D; Bwayo, JJ; Arienti, D; Zagliani, A; Mwangi, FM.; Kariuki C.; Ngugi, Elizabeth N; MacDonald KS.; Ball TB.; Clerici M.; Plummer FA. (Department of Medical Microbiology and Community Health, University of Nairobi, Nairobi, KenyaDivision of Infectious Diseases, Department of Medicine, University of Toronto, Canada,The Cattedra di Immunologia, Universita degli Studi di Milano, Milan, ItalyDepartment of Medical Microbiology, University of Manitoba, Winnipeg, Canada, 1999)
      Objectives: Most HIV-1 transmission is sexual; therefore, immune responses in the genital mucosa may be important in mediating protection against HIV infection. This study examined HIV-1-specific mucosal IgA in a cohort ...

    • A randomized, placebo-controlled trial of monthly azithromycin prophylaxis to prevent sexually transmitted infections and HIV-1 in Kenyan sex workers: study design and baseline findings 

      Fonck K; Kaul R.; Kimani J; Keli F.; MacDonald KS.; Ronald AR.; Plummer, FA; Kirui P.; Bwayo, JJ; Ngugi, Elizabeth N; Moses S.; Temmerman, M (International Center for Reproductive Health, Department of Obstetrics and Gynaecology, Ghent University, Belgium.Department of Community Health, University of Nairobi,Department of Medical Microbiology, University of NairobiDepartment of Public Health, Nairobi City CouncilDepartment of Medical Microbiology, University of Manitoba, Winnipeg, Canada, 2000)
      Our objectives were to describe the baseline findings of a trial of antibiotic prophylaxis to prevent sexually transmitted infections (STIs) and HIV-1 in a cohort of Nairobi female sex workers (FSWs). A questionnaire was ...

    • Reduced HIV risk-taking and low HIV incidence after enrollment and risk-reduction counseling in a sexually transmitted disease prevention trial in Nairobi, Kenya 

      Kaul R.; Kimani J.; Nagelkerke, NJ; Fonck, K.; Keli F.; MacDonald KS.; Ronald AR.; Plummer, FA; Bwayo JJ.; Ngugi, Elizabeth N; Temmerman, M; Moses S. (Department of Community Health, University of Nairobi,Department of Medical Microbiology, University of Manitoba, Winnipeg, Canada, 2002)
      There is an urgent need in sub-Saharan Africa to develop more effective methods of HIV prevention, including improved strategies of sexually transmitted infection (STI) prevention or an HIV vaccine. The efficacy of these ...

    • Sustained changes in sexual behavior by female sex workers after completion of a randomized HIV prevention trial 

      Ngugi, Elizabeth N; Chakkalackal, M; Sharma A.; Bukusi, EA; Njoroge B.; Kimani J.; MacDonald KS.; Bwayo, JJ; Cohen CR.; Moses S.; Kaul R. (Department of Medical Microbiology, University of Nairobi, Nairobi, Kenya, 2007)
      INTRODUCTION: Behavioral interventions in female sex workers (FSWs) are associated with changes in sexual behavior and reduced rates of sexually transmitted infections (STIs) and HIV We examined the sustainability of ...