Now showing items 1-20 of 27

    • Better Drug Therapy for the Children of Africa: Current Impediments to Success and Potential Strategies for Improvement 

      Macleod, S M; Finch, J K; Macharia, W M; Anabwani, G M (University of Nairobi.Department of Paediatrics and Child Health, College of Health Sciences, University of Nairobi, Kenya, 2013-04)
      A commentary is presented on the urgent need for a comprehensive effort to improve the practice of pediatric therapeutics in Africa. A call for action is addressed to a variety of practitioners internationally, many of ...
    • Bone involvement in childhood acute lymphoblastic leukaemia 

      Macharia, W M (University of Nairobi.Department of Human Anatomy, College of Health Sciences. University of Nairobi, Nairobi, Kenya, 1996-11)
    • Cardiac abnormalities in children with malignancies at Kenyatta National Hospital 

      Kariuki, N; Macharia, W M; Aseso, H O (University of Nairobi.Department of Paediatrics and Child Health, University of Nairobi, 1997-11)
      This was a cross-sectional survey in which 80 children with malignancies were studied at the Kenyatta National Hospital to determine cardiac status before and during cancer therapy. An equal number of age and sex matched ...
    • Ceftriaxone or HIV associated angio-oedema? Case report 

      Macharia, W M; Mbaabu, C; Wachira, L; Muhudhia, S O; Moniz, G (University of Nairobi.Department of Paediatrics and Child Health, College of Health Sciences, University of Nairobi, Kenya, 2005-11)
      Angio-oedema may be hereditary or acquired and is characterised by episodes of potentially life threatening localised tissue oedema and swelling resulting from deficiency of compliment pathway C1 esterase inhibitor. Acquired ...
    • Childhood asthma at Kenyatta National Hospital, Nairobi 

      Macharia, W M; Mirza, N M; Wafula, E M; Onyango, F E (Department of Paediatrics, University of Nairobi., 1990)
      Between January 1986 and July 1988, 356 children with bronchial asthma below 14 years of age were evaluated at the Kenyatta National Hospital. 21.3% experienced initial asthmatic attacks before the age of six months and ...
    • Childhood cancers in a referral hospital in Kenya: a review 

      Macharia, W M (University of Nairobi.Department of Paediatrics, Unversity of Nairobi, Kenya, 1996-10)
      Following the outbreak of human immune deficiency virus (HIV) infection in the early 1980's, there has been an increase in reported cases of Kaposi's sarcoma, among other childhood malignancies, from the East and Central ...
    • Childhood cancers in Kenya 

      Macharia, W M (University of Nairobi.Department of Human Anatomy, College of Health Sciences. University of Nairobi, P.O. Box 30197. Nairobi, Kenya, 1999-01)
    • Clinical presentation of atopic dermatitis in Negroid children 

      Macharia, W M; Anabwani, G M; Owili, D M (University of Nairobi.Department of Paediatrics, University of Nairobi, Kenya, 1993-12)
      Clinical findings in 54 consecutive negroid children with atopic dermatitis (AD) are presented. The age range was 0.25 to 10.25 years. Male:Female ratio was 1.2:1. Time of onset range between 1 week and 8 years with onset ...
    • Comparison of prognostic determinants in childhood acute lymphoblastic leukaemia in negroid and Caucasian populations 

      Macharia, W M (University of Nairobi.Department of Paediatrics, University of Nairobi, Kenya, 1996-10)
      The response of acute lymphoblastic leukaemia (ALL) to treatment remains very low in developing countries. Many factors have been cited to be probable determinants of prognosis. To compare the prognostic determinants of ...
    • Effects of skin contactants on evolution of atopic dermatitis in children: a case control study 

      Macharia, W M; Anabwani, G M; Owili, D M (University of Nairobi.Department of Paediatrics, University of Nairobi, Kenya, 1991-07)
      There is little published literature on the effects of skin contactants during early infancy on eventual development of atopic dermatitis (AD). The purpose of this study was to determine whether or not a relationship exists ...
    • Epidemiology of acute respiratory tract infections among young children in Kenya. 

      Wafula, E M; Onyango, F E; Mirza, W M; Macharia, W M; Wamola, I; Ndinya-Achola, J O; Agwanda, R; Waigwa, R N; Musia, J (Department of Paediatrics, University of Nairobi,, 1990)
      The epidemiology of acute respiratory tract infection (ARI) was investigated in a rural community 80 km north of Nairobi, Kenya. This research was conducted prospectively on 250 families with 470 children less than 5 years ...
    • Four-country surveillance of intestinal intussusception and diarrhoea in children 

      Awasthi, S; Agarwal, G G; Mishra, V; Nag, V L; El, Sayed H F; da, Cunha A J; Madeiro, A; Jain, D; Macharia, W M; Ndung'u, J; Awasthi, S; Wakhlu, A (University of Nairobi.Department of Paediatrics and Child Health, College of Health Sciences, University of Nairobi, Kenya, 2009-03)
      AIM: Establishment of baseline epidemiology of intussusception in developing countries has become a necessity with the possibility of reintroduction of rotavirus vaccine. The current study assessed the seasonal trend in ...
    • Highlight on childhood lymphomas 

      Macharia, W M (University of Nairobi.Department of Paediatrics, University of Nairobi, Kenya., 1996-06)
      Not Available
    • Iron deficiency anaemia in children of a peri-urban health facility. 

      Murila, F V; Macharia, W M; Wafula, E M (1999)
      To ascertain the prevalence of iron deficiency anaemia(IDA) and its risk factors. A cross-sectional survey. A peri-urban health centre in Nairobi, Kenya. Four hundred and three children, aged six months to six ...
    • Is your patient taking treatment as prescribed? 

      Macharia, W M (University of Nairobi.Department of Human Anatomy, College of Health Sciences. University of Nairobi, Kenya, 1997-09)
    • Knowledge, Attitudes and Beliefs of Primary Caretakers towards Sickle Cell Anaemia in Children. East Afr Med J. 1997 Jul;74(7):416-9. 

      Macharia, W M; Shiroya, A; Njeru, E K (University of Nairobi, 1997)
      No abstract available
    • Mortality patterns in a rural Kenyan community. 

      Mirza, N M; Macharia, W M; Wafula, E M; Agwanda, R; Onyango, F E (Department of Paediatrics, College of Health Sciences, University of Nairobi., 1990)
      Causes of death of 239 children below the age of 5 years in a rural community were determined using structured questionnaires. It was found that mortality was highest in infancy, accounting for 63% of all deaths with a ...
    • Outcome and haemato-toxicity of two chemotherapy regimens for childhood non-Hodgkin's lymphoma in a Kenyan hospital 

      Macharia, W M (Department of Paediatrics, College of Health Sciences, University of Nairobi., 2009)
      BACKGROUND: Effectiveness and toxicity of childhood cancer treatments have never been evaluated in Kenya since introduction of structured care in the early seventies. OBJECTIVE: To evaluate effectiveness and ...
    • An overview of interventions to improve compliance with appointment keeping for medical services 

      Macharia, W M; Leon, G; Rowe, B H; Stephenson, B J; Haynes, R B (University of Nairobi.Department of Paediatrics, University of Nairobi, Kenya, 1992-04)
      OBJECTIVE: To determine, by a quantitative meta-analysis of randomized trials, the effectiveness of strategies to improve patient compliance with screening, referral, and clinic appointments for health services that are ...
    • Patient safety in developing countries: retrospective estimation of scale and nature of harm to patients in hospital 

      Wilson, R M; Michel, P; Olsen, S; Gibberd, R W; Vincent, C; El-Assady, R; Rasslan, O; Qsous, S; Macharia, W M; Sahel, A; Whittaker, S; Abdo-Ali, M; Letaief, M; Ahmed, N A; Abdellatif, A; Larizgoitia, I; WHO Patient Safety EMRO/AFRO Working Group (University of Nairobi.Department of Paediatrics and Child Health, College of Health Sciences, University of Nairobi, Kenya, 2012-03)
      OBJECTIVE: To assess the frequency and nature of adverse events to patients in selected hospitals in developing or transitional economies. DESIGN: Retrospective medical record review of hospital admissions during 2005 ...