Browsing Faculty of Health Sciences (FHS) by Author "Nagelkerke, Nico J."

Now showing items 1-2 of 2

    • HIV viral set point and host immune control in individuals with HIV-specific CD8R T-cell responses prior to HIV acquisition 

      Kaul, Rupert; MacDonald, Kelly S.; Nagelkerke, Nico J.; Kimani, Joshua; Fowke, Keith; Ball, T. Blake; Luo, Ma; Kariri, Anthony; Jaoko Walter G.; Moses, Stephen; Rowland-Jones, Sarah; Plummer, Francis A (2010)
      OBJECTIVE: Vaccine-induced CD8(+) T-cell responses in primates have been associated with a reduced simian immunodeficiency virus plasma viral load and enhanced T-cell responses, but cellular vaccines have shown limited ...

    • HIV-1 Clade D Is Associated with Increased Rates of CD4 Decline in a Kenyan Cohort 

      McKinnon, Lyle R.; Nagelkerke, Nico J.; Kaul, Rupert; Shaw, Souradet Y.; Capina, Rupert; Luo, Ma; Kariri, Anthony; Apidi, Winnie; Kimani, Makobu; Wachihi, Charles; Jaoko Walter G.; Anzala Aggrey O.; Kimani, Joshua; Ball, T. Blake; Plummer, Francis A. (2012)
      HIV-1 is grouped phylogenetically into clades, which may impact rates of HIV-1 disease progression. Clade D infection in particular has been shown to be more pathogenic. Here we confirm in a Nairobi-based prospective ...