Browsing Faculty of Health Sciences (FHS) by Subject "Sex workers"

Now showing items 1-6 of 6

    • Associations of human leukocyte antigen DRB with resistance or susceptibility to HIV-1 infection in the Pumwani Sex Worker Cohort 

      Lacap, PA; Huntington, JD; Luo, M; Nagelkerke, NJ; Bielawny, T; Kimani, J; Wachihi, C; Ngugi, Elizabeth N; Plummer, FA (Department of Community Health, University of Nairobi,National Microbiology Laboratory, Winnipeg, Canada, 2008)
      OBJECTIVE: A group of commercial sex workers in the Pumwani Sex Worker Cohort, established in 1985 in Nairobi, Kenya, remain HIV-1 uninfected despite heavy exposure to HIV-1 through active sex work. Previous studies showed ...

    • Does antiretroviral therapy initiation increase sexual risk taking in Kenyan female sex workers? A retrospective case–control study 

      Mawji, Elysha; McKinnon, Lyle; Wachihi, Charles; Chege, Duncan; Thottingal, Paul; Kariri, Anthony; Plummer, Francis; Ball, Blake T; Jaoko Walter G.; Ngugi, Elizabeth N; Kimani, Joshua; Gelmon, Lawrence; Nagelkerke, Nico; Kaul, Rupert (Department of Community HealthDepartment of Medical Microbiology, 2012)
      Although antiretroviral therapy (ART) prolongs life and reduces infectiousness, in some contexts, it has been associated with increased sexual risk taking. Design Retrospective case–control study. Setting ...

    • Human leukocyte antigen-DQ alleles and haplotypes and their associations with resistance and susceptibility to HIV-1 infection 

      Hardie, RA; Luo, M; Bruneau B; Knight, E; Nagelkerke, NJ; Kimani, J; Wachihi, C; Ngugi, Elizabeth N; Plummer, FA (Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, CanadaDepartment of Community Health, University of Nairobi,Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada,Department of Community Medicine, United Arab Emirates University, Al-Ain, United Arab EmiratesMedical Microbiology, Room 507, Basic Medical Sciences Building, 730 William Avenue,, 2008)
      Objectives: To determine the association of DQ antigens with resistance and susceptibility to HIV-1. Design: Despite repeated exposure to HIV-1, a subset of women in the Pumwani Sex Worker cohort established in Nairobi, ...

    • The origins of a research community in the Majengo observational cohort study, Nairobi, Kenya 

      Bandewar, Sunita V S; Kimani, Joshua; Lavery, James V (Institute of Tropical and Infectious Diseases, 2010)
      Background Since the 1980s the Majengo Observational Cohort Study (MOCS) has examined sexually transmitted infections, in particular HIV/AIDS, in a cohort of sex workers in Majengo, an impoverished urban village in ...

    • Persistently HIV-1 seronegative Nairobi sex workers are susceptible to in vitro infection 

      Bienzle, Dorothee; MacDonald, Kelly S; Copeland, Karen F T; Bwayo, JJ; Plummer, Francis A; Rosenthal, Kenneth L (Department of Medical Microbiology, 2000)
      OBJECTIVE: To evaluate whether resistance to HIV-1 infection in a subset of highly exposed sex workers correlates with resistance at the cellular level. DESIGN: In vitro evaluation of susceptibility to infection by ...

    • Preventing HIV-1 Infection, More Epitope Is Not Better: Analysis of Gag Epitope of 2 HLA Alleles Associated with Different Outcome of HIV Infection 

      Luo, Ma; Daniuk, Christina A; Diallo, Tamsir O; Capina, Rupert E; Kimani, Joshua; Wachihi, Charles; Kimani, Makubo; Bielawny, Thomas; Peterson, Trevor; Mendoza, Mark G R; Kiazyk, Sandra; Ball, Blake T; Plummera, Francis A (Department of Medical Microbiology, 2012)
      Background: Current HIV vaccine candidates have been based on the conventional views of viral infection and attempt to induce broad T cell responses to HIV-1. Until now, the candidate vaccines based on such approach ...